Inhibition of human non-pancreatic phospholipases A2 by retinoids and flavonoids. Mechanism of action

The interaction of retinoids and flavonoids with phospholipases A2 (PLA2) was studied to assess the mechanism of inhibition. Retinoids, such as retinal, retinol, retinoic acid and retinol acetate, and flavonoids, such as quercetin, rutin, morin and sciadopitysin, inhibit Ca2+-dependent PLA2 activity...

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Veröffentlicht in:	Agents and Actions 1988-12, Vol.25 (3-4), p.394-400
Hauptverfasser:	Fawzy, A A, Vishwanath, B S, Franson, R C
Format:	Artikel
Sprache:	eng
Schlagworte:	Arthritis - enzymology Calorimetry, Differential Scanning Flavonoids - pharmacology Humans Phospholipases - antagonists & inhibitors Phospholipases A - antagonists & inhibitors Phospholipases A2 Quercetin - pharmacology Retinaldehyde - pharmacology Retinoids - pharmacology Synovial Fluid - enzymology
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