Human platelet 5-hydroxytryptamine receptors: binding of [3H]-lysergic acid diethylamide (LSD). Effects of chronic neuroleptic and antidepressant drug administration

Chronic treatment with phenothiazines and thioxanthenes has been found to enhance 5-HT-induced aggregation of human platelets. A method has been developed to study 5-HT2 receptor binding sites on platelets utilising [3H]-LSD and more recently 125I/LSD. Results are presented which suggest that the LS...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Experientia 1988-02, Vol.44 (2), p.142-145
Hauptverfasser:	Grahame-Smith, D G, Geaney, D P, Schachter, M, Elliott, J M
Format:	Artikel
Sprache:	eng
Schlagworte:	Antidepressive Agents - pharmacology Antipsychotic Agents - pharmacology Cell Membrane - metabolism Desipramine - pharmacology Humans Lysergic Acid Diethylamide - antagonists & inhibitors Lysergic Acid Diethylamide - metabolism Receptors, Serotonin - metabolism Reference Values Schizophrenia - blood Serotonin - metabolism Time Factors Tritium
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!