Monoclonal antibodies against antigens on breast cancer cells

Of 360 mAb obtained in a cell fusion experiment with the spleen cells of a mouse immunized with a mixture of different human breast carcinoma cell lines, 30 mAb were selected which reacted more strongly with tumor cells than with (noncancerous) fibroblasts. These mAb were tested for reactivity with...

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Veröffentlicht in:	Experientia 1985-11, Vol.41 (11), p.1377-1381
Hauptverfasser:	STAHLI, C, TAKACS, B, MIGGIANO, V, STAEHELIN, T, CARMANN, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal tumors. Experimental tumors Animals Antibodies, Monoclonal - immunology Antibody Specificity antigen (tumor-associated) Antigens, Neoplasm - immunology Biological and medical sciences breast Breast Neoplasms - immunology carcinoma Cell Line cell surface Epitopes - immunology Experimental genital and mammary tumors Female Fibroblasts - immunology Fluorescent Antibody Technique Histocytochemistry Humans Hybridomas - immunology Male Medical sciences Mice Mice, Inbred BALB C monoclonal antibodies Tumors
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