Treatment of drug-induced agranulocytosis with recombinant granulocyte colony-stimulating factor (rh G-CSF)

Five patients with drug-induced agranulocytosis received 300 micrograms recombinant human granulocyte colony-stimulating factor (rh G-CSF) subcutaneously twice daily for 2-5 days. G-CSF therapy resulted in a steep increase of the neutrophil count, which was faster than that in patients with spontane...

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Veröffentlicht in:	Annals of hematology 1993-05, Vol.66 (5), p.241-244
Hauptverfasser:	WILLFORT, A, LORBER, C, KAPIOTIS, S, SERTL, S, HAINZ, R, KIRCHWEGER, P, JÄGER, U, KYRLE, P. A, LECHNER, K, GEISSLER, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Agranulocytosis - chemically induced Agranulocytosis - drug therapy Biological and medical sciences Dipyrone - adverse effects Female Granulocyte Colony-Stimulating Factor - administration & dosage Granulocyte Colony-Stimulating Factor - therapeutic use Humans Immunomodulators Male Medical sciences Methimazole - adverse effects Middle Aged Pharmacology. Drug treatments Recombinant Proteins - administration & dosage Recombinant Proteins - therapeutic use
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