A randomized multicentric study comparing alternating combination chemotherapy (VCMP/VBAP) and melphalan-prednisone in multiple myeloma

Between January 1985 and December 1988, 386 patients with multiple myeloma were randomized to receive either MP or combination chemotherapy based on alternating cycles of VCMP and VBAP. The major prognostic parameters did not differ significantly between both treatment groups. A significantly higher...

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Veröffentlicht in:	Blut 1990-06, Vol.60 (6), p.319-322
Hauptverfasser:	BLADE, J, SAN MIGUEL, J, HERNANDEZ MARTIN, J.M, BESALDUCH, J, HERNANDEZ NIETO, L, FERNANDEZ CALVO, J, RUBIO, D, MAYANS, J. R, SANCHIS, J, JIMENEZ GALINDO, R, TORTOSA, J, ORTEGA, F, ALCALA, A, MALDONADO, J, GARCIA-CONDE, J, MORO, M. J, SANZ SANZ, M. A, ALONSO, C, ZUBIZARRETA, A, BESSES, C
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic agents Antineoplastic Combined Chemotherapy Protocols - therapeutic use Biological and medical sciences Carmustine - administration & dosage Chemotherapy Cyclophosphamide - administration & dosage Doxorubicin - administration & dosage Drug Administration Schedule Female Humans Male Medical sciences Melphalan - administration & dosage Middle Aged Multicenter Studies as Topic Multiple Myeloma - drug therapy Multiple Myeloma - mortality Pharmacology. Drug treatments Prednisone - administration & dosage Prospective Studies Randomized Controlled Trials as Topic Vincristine - administration & dosage
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