Immunomodulation of cimetidine in healthy volunteers

The effect of cimetidine, a histamine H2-receptor antagonist, on the immune system in man was investigated in 11 healthy volunteers. Cimetidine was administered orally in daily doses of 800 mg for a period of 7 days. At the end of the administration period the number of peripheral CD8+ (cytotoxic/su...

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Veröffentlicht in:	Klinische Wochenschrift 1989-01, Vol.67 (1), p.26-30
Hauptverfasser:	Brockmeyer, N H, Kreuzfelder, E, Bluhm, C, Shen, G, Scheiermann, E, Keinecke, H O, Ohnhaus, E E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antibodies, Monoclonal Antibody Formation - drug effects Cells, Cultured Cimetidine - pharmacology Female Humans Immunity, Cellular - drug effects Intradermal Tests Lymphocyte Activation - drug effects Male T-Lymphocytes, Helper-Inducer - drug effects T-Lymphocytes, Regulatory - drug effects
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