The role of the tubulointerstitial changes in the prognosis of IgA glomerulonephritis
The authors investigated the tubulointerstitial changes (atrophic tubuli, interstitial fibrosis and round-cell infiltration) by two methods in renal biopsies from 56 patients with IgA glomerulonephritis. A statistically significant correlation was found to exist between the tubulointerstitial change...
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Veröffentlicht in: | Klinische Wochenschrift 1984-11, Vol.62 (22), p.1094-1096 |
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creator | Nagy, J Trinn, C Deák, G Schmelzer, M Burger, T |
description | The authors investigated the tubulointerstitial changes (atrophic tubuli, interstitial fibrosis and round-cell infiltration) by two methods in renal biopsies from 56 patients with IgA glomerulonephritis. A statistically significant correlation was found to exist between the tubulointerstitial changes and serum creatinine level at the time of renal biopsy. A statistical significant correlation was also established between serum creatinine at the end of a period of 5 years of follow-up and tubulointerstitial changes. Their results suggest that severe tubulointerstitial lesions in IgA glomerulonephritis carry a poor prognosis. |
doi_str_mv | 10.1007/BF01711380 |
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A statistically significant correlation was found to exist between the tubulointerstitial changes and serum creatinine level at the time of renal biopsy. A statistical significant correlation was also established between serum creatinine at the end of a period of 5 years of follow-up and tubulointerstitial changes. Their results suggest that severe tubulointerstitial lesions in IgA glomerulonephritis carry a poor prognosis.</description><identifier>ISSN: 0023-2173</identifier><identifier>EISSN: 1432-1440</identifier><identifier>DOI: 10.1007/BF01711380</identifier><identifier>PMID: 6513436</identifier><language>eng</language><publisher>Germany</publisher><subject>Adolescent ; Adult ; Biopsy ; Creatinine - blood ; Female ; Glomerular Filtration Rate ; Glomerulonephritis, IGA - pathology ; Humans ; Kidney Tubules - pathology ; Male ; Middle Aged ; Nephritis, Interstitial - pathology ; Prognosis</subject><ispartof>Klinische Wochenschrift, 1984-11, Vol.62 (22), p.1094-1096</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c282t-f8eca5568063e5f13e3dc8006951426f05aa60c73738f31cc6eda88ec6e96cfa3</citedby><cites>FETCH-LOGICAL-c282t-f8eca5568063e5f13e3dc8006951426f05aa60c73738f31cc6eda88ec6e96cfa3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6513436$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nagy, J</creatorcontrib><creatorcontrib>Trinn, C</creatorcontrib><creatorcontrib>Deák, G</creatorcontrib><creatorcontrib>Schmelzer, M</creatorcontrib><creatorcontrib>Burger, T</creatorcontrib><title>The role of the tubulointerstitial changes in the prognosis of IgA glomerulonephritis</title><title>Klinische Wochenschrift</title><addtitle>Klin Wochenschr</addtitle><description>The authors investigated the tubulointerstitial changes (atrophic tubuli, interstitial fibrosis and round-cell infiltration) by two methods in renal biopsies from 56 patients with IgA glomerulonephritis. A statistically significant correlation was found to exist between the tubulointerstitial changes and serum creatinine level at the time of renal biopsy. A statistical significant correlation was also established between serum creatinine at the end of a period of 5 years of follow-up and tubulointerstitial changes. Their results suggest that severe tubulointerstitial lesions in IgA glomerulonephritis carry a poor prognosis.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Biopsy</subject><subject>Creatinine - blood</subject><subject>Female</subject><subject>Glomerular Filtration Rate</subject><subject>Glomerulonephritis, IGA - pathology</subject><subject>Humans</subject><subject>Kidney Tubules - pathology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Nephritis, Interstitial - pathology</subject><subject>Prognosis</subject><issn>0023-2173</issn><issn>1432-1440</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1984</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkL9PwzAQhS0EKqWwsCNlYkAKnHPxj45QUahUiaWdI9c9p0FJXOxk4L8npRVM94bvezo9xm45PHIA9fQyB644Rw1nbMxzzFKe53DOxgAZphlXeMmuYvwEEJlScsRGUnDMUY7ZerWjJPiaEu-Sbshdv-lrX7UdhdhVXWXqxO5MW1JMqvaX2Adftj5W8aAsyuekrH1DYbBa2u_C4MRrduFMHenmdCdsPX9dzd7T5cfbYva8TG2msy51mqwRQmqQSMJxJNxaDSCngueZdCCMkWAVKtQOubWStkYPkqSptM7ghN0fe4efvnqKXdFU0VJdm5Z8HwslNOYC9AA-HEEbfIyBXLEPVWPCd8GhOGxY_G84wHen1n7T0PYPPY2GP1BTbEc</recordid><startdate>19841115</startdate><enddate>19841115</enddate><creator>Nagy, J</creator><creator>Trinn, C</creator><creator>Deák, G</creator><creator>Schmelzer, M</creator><creator>Burger, T</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19841115</creationdate><title>The role of the tubulointerstitial changes in the prognosis of IgA glomerulonephritis</title><author>Nagy, J ; Trinn, C ; Deák, G ; Schmelzer, M ; Burger, T</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c282t-f8eca5568063e5f13e3dc8006951426f05aa60c73738f31cc6eda88ec6e96cfa3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1984</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Biopsy</topic><topic>Creatinine - blood</topic><topic>Female</topic><topic>Glomerular Filtration Rate</topic><topic>Glomerulonephritis, IGA - pathology</topic><topic>Humans</topic><topic>Kidney Tubules - pathology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Nephritis, Interstitial - pathology</topic><topic>Prognosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nagy, J</creatorcontrib><creatorcontrib>Trinn, C</creatorcontrib><creatorcontrib>Deák, G</creatorcontrib><creatorcontrib>Schmelzer, M</creatorcontrib><creatorcontrib>Burger, T</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Klinische Wochenschrift</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nagy, J</au><au>Trinn, C</au><au>Deák, G</au><au>Schmelzer, M</au><au>Burger, T</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The role of the tubulointerstitial changes in the prognosis of IgA glomerulonephritis</atitle><jtitle>Klinische Wochenschrift</jtitle><addtitle>Klin Wochenschr</addtitle><date>1984-11-15</date><risdate>1984</risdate><volume>62</volume><issue>22</issue><spage>1094</spage><epage>1096</epage><pages>1094-1096</pages><issn>0023-2173</issn><eissn>1432-1440</eissn><abstract>The authors investigated the tubulointerstitial changes (atrophic tubuli, interstitial fibrosis and round-cell infiltration) by two methods in renal biopsies from 56 patients with IgA glomerulonephritis. A statistically significant correlation was found to exist between the tubulointerstitial changes and serum creatinine level at the time of renal biopsy. A statistical significant correlation was also established between serum creatinine at the end of a period of 5 years of follow-up and tubulointerstitial changes. Their results suggest that severe tubulointerstitial lesions in IgA glomerulonephritis carry a poor prognosis.</abstract><cop>Germany</cop><pmid>6513436</pmid><doi>10.1007/BF01711380</doi><tpages>3</tpages></addata></record> |
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subjects | Adolescent Adult Biopsy Creatinine - blood Female Glomerular Filtration Rate Glomerulonephritis, IGA - pathology Humans Kidney Tubules - pathology Male Middle Aged Nephritis, Interstitial - pathology Prognosis |
title | The role of the tubulointerstitial changes in the prognosis of IgA glomerulonephritis |
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