Immunohistochemical localization of c-erbB-2 protein and epidermal growth factor receptor in normal surface epithelium, surface inclusion cysts, and common epithelial tumours of the ovary

The c-erbB-2 (HER-2/neu) protein is a membrane glycoprotein growth factor receptor showing molecular homology with the epidermal growth factor receptor (EGFR). We examined the immunohistochemical reactivity of monoclonal antibodies against both of these proteins in normal surface epithelium, surface...

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Veröffentlicht in:	Virchows Archiv A Pathological Anatomy and Histopathology 1992-09, Vol.421 (5), p.393-400
Hauptverfasser:	Wang, D P, Konishi, I, Koshiyama, M, Nanbu, Y, Iwai, T, Nonogaki, H, Mori, T, Fujii, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Antibodies, Monoclonal Carcinoma - chemistry Carcinoma - pathology Carcinoma - ultrastructure Cell Transformation, Neoplastic - metabolism Cell Transformation, Neoplastic - pathology Epithelium - chemistry Epithelium - pathology Epithelium - ultrastructure ErbB Receptors - analysis Female Humans Immunohistochemistry Middle Aged Ovarian Cysts - chemistry Ovarian Cysts - pathology Ovarian Cysts - ultrastructure Ovarian Neoplasms - chemistry Ovarian Neoplasms - pathology Ovarian Neoplasms - ultrastructure Ovary - chemistry Ovary - pathology Ovary - ultrastructure Proto-Oncogene Proteins - analysis Receptor, ErbB-2
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