Possible role of oxygen free radicals in ethanol-induced gastric mucosal damage in rats

The involvement of oxygen free radicals in the development of the ethanol-induced gastric mucosal damage has been investigated. We found that oral administration of superoxide dismutase reduced the incidence of ethanol-induced mucosal lesions. Reduction of superoxide dismutase activity by diethyldit...

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Veröffentlicht in:	Digestive diseases and sciences 1988-07, Vol.33 (7), p.865-871
Hauptverfasser:	SZELENYI, I, BRUNE, K
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcoholism and acute alcohol poisoning Animals Antioxidants - therapeutic use Biological and medical sciences Ethanol - toxicity Free Radicals Gastric Mucosa - drug effects Indomethacin - therapeutic use Male Medical sciences Oxygen - toxicity Premedication Rats Rats, Inbred Strains Superoxide Dismutase - therapeutic use Toxicology
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