Failure of 5-aminosalicylic acid enemas to improve chronic radiation proctitis

Radiation proctitis is a well-known complication of abdominal and pelvic radiation. Conventional medical and surgical treatment often is disappointing. 5-Aminosalicylic acid (5-ASA) is the active component in sulfasalazine and is effective in the treatment of distal ulcerative colitis. Four patients...

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Veröffentlicht in:	Dig. Dis. Sci.; (United States) 1989-05, Vol.34 (5), p.758-760
Hauptverfasser:	BAUM, C. A, BIDDLE, W. L, MINER, P. B. JR
Format:	Artikel
Sprache:	eng
Schlagworte:	560151 - Radiation Effects on Animals- Man ABDOMEN Aminosalicylic Acids - administration & dosage Biological and medical sciences BIOLOGICAL EFFECTS BIOLOGICAL RADIATION EFFECTS BODY BODY AREAS CARBOXYLIC ACIDS Chronic Disease Digestive system DIGESTIVE SYSTEM DISEASES DISEASES Drug Evaluation Enema - methods Female Humans HYDROXY ACIDS INJURIES Male Medical sciences MEDICINE Mesalamine NUCLEAR MEDICINE ORGANIC ACIDS ORGANIC COMPOUNDS PATIENTS PELVIS Pharmacology. Drug treatments PROCTITIS Proctitis - diagnosis Proctitis - drug therapy Proctitis - etiology RADIATION EFFECTS RADIATION INJURIES Radiation Injuries - diagnosis Radiation Injuries - drug therapy Radiation Injuries - etiology RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT RADIOINDUCTION RADIOLOGY RADIOSENSITIVITY EFFECTS RADIOTHERAPY SALICYLIC ACID SIDE EFFECTS Sigmoidoscopy THERAPY
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