Effects of oral agents on pancreatic duct permeability: a model of acute alcoholic pancreatitis

The main pancreatic duct can be made permeable to molecules of up to 20,000 daltons by oral pretreatment with aspirin and ethanol. Because pancreatic enzymes have similar molecular weights, we hypothesized that activated pancreatic enzymes would leak from a permeable duct and produce pancreatitis. F...

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Veröffentlicht in:	Digestive diseases and sciences 1986-10, Vol.31 (10), p.1081-1088
Hauptverfasser:	WEDGWOOD, K. R, ADLER, G, KERN, H, REBER, H. A
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Alcoholism - complications Alcoholism and acute alcohol poisoning Animals Aspirin - pharmacology Biological and medical sciences Cats Cell Membrane Permeability - drug effects Ethanol - pharmacology Medical sciences Pancreatic Ducts - drug effects Pancreatic Juice Pancreatitis - etiology Perfusion Toxicology
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