Striatal and extrastriatal imaging of dopamine D2 receptors in the living human brain with [123I]epidepride single-photon emission tomography

The iodine-123 labelled ligand benzamide epidepride was evaluated as a probe for in vivo imaging of striatal and extrastriatal dopamine D2 receptor sites in the human brain. Four healthy males were imaged with a high-resolution single-photon emission tomography scanner. Striatal radioactivity peaked...

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Veröffentlicht in:	European Journal of Nuclear Medicine 1997-05, Vol.24 (5), p.483-487
Hauptverfasser:	KUIKKA, J. T, AKERMAN, K. K, HILTUNEN, J, BERGSTRÖM, K. A, RÄSÄNEN, P, VANNINEN, E, HALLDIN, C, TIIHONEN, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Benzamides - pharmacokinetics Biological and medical sciences Brain - diagnostic imaging Corpus Striatum - diagnostic imaging Humans Investigative techniques, diagnostic techniques (general aspects) Iodine Radioisotopes Male Medical sciences Middle Aged Nervous system Pyrrolidines - pharmacokinetics Radionuclide investigations Receptors, Dopamine D2 - analysis Tomography, Emission-Computed, Single-Photon - methods
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