Peripheral acting muscle relaxants alter the effects of baclofen on the electrocorticograms in the rat

The effects of intraperitoneally administered baclofen on behavior and electrocorticograms (ECoG) were studied in freely moving and paralyzed rats. In the freely moving rats, 10 mg/kg of baclofen suppressed ECoGs with behavioral sedation, and 20 mg/kg caused whole body twitching accompanied with spi...

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Veröffentlicht in:	Journal of Neural Transmission 1992-02, Vol.87 (1), p.37-47
Hauptverfasser:	YOKOI, I, AKIYAMA, K, KABUTO, H, FUKUYAMA, K, NISHIJIMA, Y, MORI, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Baclofen - antagonists & inhibitors Baclofen - pharmacology Behavior, Animal - drug effects Biological and medical sciences Electroencephalography - drug effects Electromyography - drug effects Gabaergic and benzodiazepinic system Gallamine Triethiodide - pharmacology Male Medical sciences Neuromuscular Depolarizing Agents - pharmacology Neuromuscular Nondepolarizing Agents - pharmacology Neuropharmacology Neurotransmitters. Neurotransmission. Receptors Pancuronium - pharmacology Pharmacology. Drug treatments Rats Rats, Inbred Strains Stereotaxic Techniques Succinylcholine - pharmacology Tubocurarine - pharmacology
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