Characterization of an established human, malignant, glioblastoma cell line (GBM) and its response to conventional drugs

A cell line, GBM, was established from a human malignant glioblastoma and was characterized with particular reference to its response to conventional drugs. The GBM cell line exhibited a 73 +/- 7 h doubling time in monolayer cultures. Expression of glial fibrillary acidic and S-100 proteins was obse...

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Veröffentlicht in:	Journal of cancer research and clinical oncology 1994-10, Vol.120 (10), p.585-592
Hauptverfasser:	PEREGO, P, BOIARDI, A, ZUNINO, F, CARENINI, N, DE CESARE, M, DOLFINI, E, GIARDINI, R, MAGNANI, I, MARTIGNONE, S, SILVANI, A, SORANZO, C
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic agents Antineoplastic Agents - toxicity Biological and medical sciences Biopsy Cell Cycle - drug effects Cell Division - drug effects Cell Line Chromosome Banding Culture Techniques - methods gamma-Glutamyltransferase - metabolism General aspects Glioblastoma - genetics Glioblastoma - pathology Glutathione - metabolism Humans Karyotyping Male Medical sciences Mice Mice, Nude Middle Aged Pharmacology. Drug treatments Transplantation, Heterologous Tumor Cells, Cultured
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