Atypical multidrug resistance in human ovarian cancer cell line A2780 selected for resistance to doxorubicin (A2780 DX3)

Human ovarian cancer cells A2780, selected for resistance to doxorubicin (A2780-DX3), are cross-resistant to various other topoisomerase-II-targeted drugs but not to vinblastine. The parental cell line was very sensitive to doxorubicin-, mitoxantrone- or etoposide(VP16)-induced DNA single-strand bre...

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Veröffentlicht in:	Journal of cancer research and clinical oncology 1995-03, Vol.121 (3), p.155-163
Hauptverfasser:	CIMOLI, G, VALENTI, M, NOVIELLO, E, PARODI, S, MAZZONI, A, ROVINI, E, DE SESSA, F, RUSSO, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic agents Antineoplastic Agents - pharmacology Biological and medical sciences Catalysis Cell Survival - drug effects DNA Damage DNA Topoisomerases, Type II - metabolism Doxorubicin - pharmacology Drug Resistance, Multiple Etoposide - pharmacology Female General aspects Humans Medical sciences Mitoxantrone - pharmacology Ovarian Neoplasms - drug therapy Pharmacology. Drug treatments Tumor Cells, Cultured
Online-Zugang:	Volltext
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