Ultrastructure of the human preovulatory oocyte
The ultrastructure of preovulatory human oocyte-cumulus complexes was described after inducing maturation by clomiphene, human menopausal gonadotropin (hMG), human chorionic gonadotropin (hCG) treatment. The majority of the oocytes was at metaphase II of meiosis, with a radially orientated spindle....
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Veröffentlicht in: | Journal of In Vitro Fertilization and Embryo Transfer 1986-08, Vol.3 (4), p.232-242 |
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container_title | Journal of In Vitro Fertilization and Embryo Transfer |
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creator | SZOLLOSI, D MANDELBAUM, J PLACHOT, M SALAT-BAROUX, J COHEN, J |
description | The ultrastructure of preovulatory human oocyte-cumulus complexes was described after inducing maturation by clomiphene, human menopausal gonadotropin (hMG), human chorionic gonadotropin (hCG) treatment. The majority of the oocytes was at metaphase II of meiosis, with a radially orientated spindle. The oocyte surface was covered by a multitude of microvilli. Cortical granules were nonuniformly distributed along the cortex. A cytoplasmic polarization was observed. The cytoplasmic organelles were in general uniformly dispersed, with the exception of a narrow segment within which cytoplasmic membranes and mitochondria formed clusters. The spindle was usually found at the borderline between the two regions of the cytoplasm. The functional significance of this polarization is not yet known. |
doi_str_mv | 10.1007/bf01132810 |
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The majority of the oocytes was at metaphase II of meiosis, with a radially orientated spindle. The oocyte surface was covered by a multitude of microvilli. Cortical granules were nonuniformly distributed along the cortex. A cytoplasmic polarization was observed. The cytoplasmic organelles were in general uniformly dispersed, with the exception of a narrow segment within which cytoplasmic membranes and mitochondria formed clusters. The spindle was usually found at the borderline between the two regions of the cytoplasm. The functional significance of this polarization is not yet known.</description><identifier>ISSN: 0740-7769</identifier><identifier>EISSN: 2331-3315</identifier><identifier>EISSN: 1573-7330</identifier><identifier>DOI: 10.1007/bf01132810</identifier><identifier>PMID: 3093615</identifier><identifier>CODEN: JFETDC</identifier><language>eng</language><publisher>New York, NY: Plenum</publisher><subject>Biological and medical sciences ; Birth control ; Chorionic Gonadotropin - pharmacology ; Clomiphene - pharmacology ; Female ; Fertility Agents, Female - pharmacology ; Follicular Phase ; Gynecology. Andrology. Obstetrics ; Humans ; Medical sciences ; Meiosis - drug effects ; Menotropins - pharmacology ; Microscopy, Electron ; Oocytes - drug effects ; Oocytes - ultrastructure ; Ovarian Follicle - ultrastructure ; Sterility. Assisted procreation ; Zona Pellucida - ultrastructure</subject><ispartof>Journal of In Vitro Fertilization and Embryo Transfer, 1986-08, Vol.3 (4), p.232-242</ispartof><rights>1987 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c292t-5777f46e217119083da7999173740b7c0425ed8f62070642bc40344c40b7ca263</citedby><cites>FETCH-LOGICAL-c292t-5777f46e217119083da7999173740b7c0425ed8f62070642bc40344c40b7ca263</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=8049899$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3093615$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>SZOLLOSI, D</creatorcontrib><creatorcontrib>MANDELBAUM, J</creatorcontrib><creatorcontrib>PLACHOT, M</creatorcontrib><creatorcontrib>SALAT-BAROUX, J</creatorcontrib><creatorcontrib>COHEN, J</creatorcontrib><title>Ultrastructure of the human preovulatory oocyte</title><title>Journal of In Vitro Fertilization and Embryo Transfer</title><addtitle>J In Vitro Fert Embryo Transf</addtitle><description>The ultrastructure of preovulatory human oocyte-cumulus complexes was described after inducing maturation by clomiphene, human menopausal gonadotropin (hMG), human chorionic gonadotropin (hCG) treatment. The majority of the oocytes was at metaphase II of meiosis, with a radially orientated spindle. The oocyte surface was covered by a multitude of microvilli. Cortical granules were nonuniformly distributed along the cortex. A cytoplasmic polarization was observed. The cytoplasmic organelles were in general uniformly dispersed, with the exception of a narrow segment within which cytoplasmic membranes and mitochondria formed clusters. The spindle was usually found at the borderline between the two regions of the cytoplasm. The functional significance of this polarization is not yet known.</description><subject>Biological and medical sciences</subject><subject>Birth control</subject><subject>Chorionic Gonadotropin - pharmacology</subject><subject>Clomiphene - pharmacology</subject><subject>Female</subject><subject>Fertility Agents, Female - pharmacology</subject><subject>Follicular Phase</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Medical sciences</subject><subject>Meiosis - drug effects</subject><subject>Menotropins - pharmacology</subject><subject>Microscopy, Electron</subject><subject>Oocytes - drug effects</subject><subject>Oocytes - ultrastructure</subject><subject>Ovarian Follicle - ultrastructure</subject><subject>Sterility. Assisted procreation</subject><subject>Zona Pellucida - ultrastructure</subject><issn>0740-7769</issn><issn>2331-3315</issn><issn>1573-7330</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kEFLw0AQRhdRaqm9eBdyEA9C7MzuJpM9arEqFLzYc9hsN7SSdOvuRui_N9rYgWEO7_ExfIxdIzwgAM2qGhAFLxDO2JgLgWm_2TkbA0lIiXJ1yaYhfEI_QglEPmIjAUrkmI3ZbNVEr0P0nYmdt4mrk7ixyaZr9S7Ze-u-u0ZH5w-Jc-YQ7RW7qHUT7HS4E7ZaPH_MX9Pl-8vb_HGZGq54TDMiqmVuORKigkKsNSmlkET_VEUGJM_suqhzDgS55JWRIKQ0f1DzXEzY3TF3791XZ0Ms220wtmn0zroulESQUZZhL94fReNdCN7W5d5vW-0PJUL5W1D5tPgvqJdvhtSuau36pA519Px24DoY3dRe78w2nLQCpCqUEj8YW2nt</recordid><startdate>198608</startdate><enddate>198608</enddate><creator>SZOLLOSI, D</creator><creator>MANDELBAUM, J</creator><creator>PLACHOT, M</creator><creator>SALAT-BAROUX, J</creator><creator>COHEN, J</creator><general>Plenum</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>198608</creationdate><title>Ultrastructure of the human preovulatory oocyte</title><author>SZOLLOSI, D ; MANDELBAUM, J ; PLACHOT, M ; SALAT-BAROUX, J ; COHEN, J</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c292t-5777f46e217119083da7999173740b7c0425ed8f62070642bc40344c40b7ca263</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Biological and medical sciences</topic><topic>Birth control</topic><topic>Chorionic Gonadotropin - pharmacology</topic><topic>Clomiphene - pharmacology</topic><topic>Female</topic><topic>Fertility Agents, Female - pharmacology</topic><topic>Follicular Phase</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Medical sciences</topic><topic>Meiosis - drug effects</topic><topic>Menotropins - pharmacology</topic><topic>Microscopy, Electron</topic><topic>Oocytes - drug effects</topic><topic>Oocytes - ultrastructure</topic><topic>Ovarian Follicle - ultrastructure</topic><topic>Sterility. Assisted procreation</topic><topic>Zona Pellucida - ultrastructure</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SZOLLOSI, D</creatorcontrib><creatorcontrib>MANDELBAUM, J</creatorcontrib><creatorcontrib>PLACHOT, M</creatorcontrib><creatorcontrib>SALAT-BAROUX, J</creatorcontrib><creatorcontrib>COHEN, J</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of In Vitro Fertilization and Embryo Transfer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SZOLLOSI, D</au><au>MANDELBAUM, J</au><au>PLACHOT, M</au><au>SALAT-BAROUX, J</au><au>COHEN, J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ultrastructure of the human preovulatory oocyte</atitle><jtitle>Journal of In Vitro Fertilization and Embryo Transfer</jtitle><addtitle>J In Vitro Fert Embryo Transf</addtitle><date>1986-08</date><risdate>1986</risdate><volume>3</volume><issue>4</issue><spage>232</spage><epage>242</epage><pages>232-242</pages><issn>0740-7769</issn><eissn>2331-3315</eissn><eissn>1573-7330</eissn><coden>JFETDC</coden><abstract>The ultrastructure of preovulatory human oocyte-cumulus complexes was described after inducing maturation by clomiphene, human menopausal gonadotropin (hMG), human chorionic gonadotropin (hCG) treatment. The majority of the oocytes was at metaphase II of meiosis, with a radially orientated spindle. The oocyte surface was covered by a multitude of microvilli. Cortical granules were nonuniformly distributed along the cortex. A cytoplasmic polarization was observed. The cytoplasmic organelles were in general uniformly dispersed, with the exception of a narrow segment within which cytoplasmic membranes and mitochondria formed clusters. The spindle was usually found at the borderline between the two regions of the cytoplasm. The functional significance of this polarization is not yet known.</abstract><cop>New York, NY</cop><pub>Plenum</pub><pmid>3093615</pmid><doi>10.1007/bf01132810</doi><tpages>11</tpages></addata></record> |
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subjects | Biological and medical sciences Birth control Chorionic Gonadotropin - pharmacology Clomiphene - pharmacology Female Fertility Agents, Female - pharmacology Follicular Phase Gynecology. Andrology. Obstetrics Humans Medical sciences Meiosis - drug effects Menotropins - pharmacology Microscopy, Electron Oocytes - drug effects Oocytes - ultrastructure Ovarian Follicle - ultrastructure Sterility. Assisted procreation Zona Pellucida - ultrastructure |
title | Ultrastructure of the human preovulatory oocyte |
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