Stimulus-activated changes in brain tissue temperature in the anesthetized rat
A new thin-film, multisensor probe was used to determine tissue oxygen tension, tissue temperature, and electrical activity at two depths below the brain surface in chloral hydrate- or nitrous oxide/halothane-anesthetized rats. Brain tissue temperature at both depths was found to be lower than core...
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| Veröffentlicht in: | Metabolic brain disease 1989-12, Vol.4 (4), p.225-237 |
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| container_title | Metabolic brain disease |
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| creator | LAMANNA, J. C MCCRACKEN, K. A PATIL, M PROHASKA, O. J |
| description | A new thin-film, multisensor probe was used to determine tissue oxygen tension, tissue temperature, and electrical activity at two depths below the brain surface in chloral hydrate- or nitrous oxide/halothane-anesthetized rats. Brain tissue temperature at both depths was found to be lower than core temperature by 1-2 degrees C. Electrical activation, spreading depression, and pentylenetetrazol seizures all resulted in transient increases of brain tissue temperature of a few tenths degree centigrade. Vasodilation, induced by hypercapnia or hypoxia, caused a warming of brain tissue. Near-maximum oxygen metabolism, reached upon reoxygenation after severe hypoxia, was accompanied by tissue temperature rises of greater than 1 degree C. It was concluded that brain tissue temperature in the anesthetized rat is lower than core temperature due to extensive radiative and conductive heat loss to the environment through the head. Transient increases in tissue temperature during activation are caused by vasodilation and increased metabolism. |
| doi_str_mv | 10.1007/bf00999769 |
| format | Article |
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It was concluded that brain tissue temperature in the anesthetized rat is lower than core temperature due to extensive radiative and conductive heat loss to the environment through the head. Transient increases in tissue temperature during activation are caused by vasodilation and increased metabolism.</description><identifier>ISSN: 0885-7490</identifier><identifier>EISSN: 1573-7365</identifier><identifier>DOI: 10.1007/bf00999769</identifier><identifier>PMID: 2601641</identifier><identifier>CODEN: MBDIEE</identifier><language>eng</language><publisher>New York, NY: Springer</publisher><subject>Anesthesia ; Animals ; Biochemistry and metabolism ; Biological and medical sciences ; Body Temperature - physiology ; Brain - blood supply ; Brain - physiopathology ; Central nervous system ; Chloral Hydrate ; Electric Stimulation ; Electroencephalography ; Fundamental and applied biological sciences. Psychology ; Halothane ; Hypercapnia - physiopathology ; Hypoxia - physiopathology ; Nitrous Oxide ; Pentylenetetrazole ; Rats ; Seizures - chemically induced ; Seizures - physiopathology ; Vasodilation ; Vertebrates: nervous system and sense organs</subject><ispartof>Metabolic brain disease, 1989-12, Vol.4 (4), p.225-237</ispartof><rights>1990 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c377t-858cbe4eb715573d117c9b2125abfc77d2fd7ccacfa143df9bd2fbfe3584ffeb3</citedby><cites>FETCH-LOGICAL-c377t-858cbe4eb715573d117c9b2125abfc77d2fd7ccacfa143df9bd2fbfe3584ffeb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,27911,27912</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=6927350$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2601641$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>LAMANNA, J. C</creatorcontrib><creatorcontrib>MCCRACKEN, K. A</creatorcontrib><creatorcontrib>PATIL, M</creatorcontrib><creatorcontrib>PROHASKA, O. J</creatorcontrib><title>Stimulus-activated changes in brain tissue temperature in the anesthetized rat</title><title>Metabolic brain disease</title><addtitle>Metab Brain Dis</addtitle><description>A new thin-film, multisensor probe was used to determine tissue oxygen tension, tissue temperature, and electrical activity at two depths below the brain surface in chloral hydrate- or nitrous oxide/halothane-anesthetized rats. Brain tissue temperature at both depths was found to be lower than core temperature by 1-2 degrees C. Electrical activation, spreading depression, and pentylenetetrazol seizures all resulted in transient increases of brain tissue temperature of a few tenths degree centigrade. Vasodilation, induced by hypercapnia or hypoxia, caused a warming of brain tissue. Near-maximum oxygen metabolism, reached upon reoxygenation after severe hypoxia, was accompanied by tissue temperature rises of greater than 1 degree C. It was concluded that brain tissue temperature in the anesthetized rat is lower than core temperature due to extensive radiative and conductive heat loss to the environment through the head. Transient increases in tissue temperature during activation are caused by vasodilation and increased metabolism.</description><subject>Anesthesia</subject><subject>Animals</subject><subject>Biochemistry and metabolism</subject><subject>Biological and medical sciences</subject><subject>Body Temperature - physiology</subject><subject>Brain - blood supply</subject><subject>Brain - physiopathology</subject><subject>Central nervous system</subject><subject>Chloral Hydrate</subject><subject>Electric Stimulation</subject><subject>Electroencephalography</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Halothane</subject><subject>Hypercapnia - physiopathology</subject><subject>Hypoxia - physiopathology</subject><subject>Nitrous Oxide</subject><subject>Pentylenetetrazole</subject><subject>Rats</subject><subject>Seizures - chemically induced</subject><subject>Seizures - physiopathology</subject><subject>Vasodilation</subject><subject>Vertebrates: nervous system and sense organs</subject><issn>0885-7490</issn><issn>1573-7365</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1989</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kEFLxDAQRoMo67p68S704EmoJk3TNEddXBUWPajnMkknbqStS5IK-uvNsuteZmDem2H4CDln9JpRKm-0pVQpJSt1QKZMSJ5LXolDMqV1LXJZKnpMTkL4pJRywdSETIqKsqpkU_L8Gl0_dmPIwUT3DRHbzKxg-MCQuSHTHlKNLoQRs4j9Gj3E0eOGxRVmMGBIPbrftJfQKTmy0AU82_UZeV_cv80f8-XLw9P8dpkbLmXMa1EbjSVqyUR6t2VMGqULVgjQ1kjZFraVxoCxwEreWqXTRFvkoi6tRc1n5Gp71_ivEDzaZu1dD_6nYbTZZNLcLf4zSfLFVl6Pusd2r-5CSPxyxyEY6KyHwbiw1ypVSC4o_wNh4GsB</recordid><startdate>19891201</startdate><enddate>19891201</enddate><creator>LAMANNA, J. C</creator><creator>MCCRACKEN, K. A</creator><creator>PATIL, M</creator><creator>PROHASKA, O. J</creator><general>Springer</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>19891201</creationdate><title>Stimulus-activated changes in brain tissue temperature in the anesthetized rat</title><author>LAMANNA, J. C ; MCCRACKEN, K. A ; PATIL, M ; PROHASKA, O. 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Psychology</topic><topic>Halothane</topic><topic>Hypercapnia - physiopathology</topic><topic>Hypoxia - physiopathology</topic><topic>Nitrous Oxide</topic><topic>Pentylenetetrazole</topic><topic>Rats</topic><topic>Seizures - chemically induced</topic><topic>Seizures - physiopathology</topic><topic>Vasodilation</topic><topic>Vertebrates: nervous system and sense organs</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>LAMANNA, J. C</creatorcontrib><creatorcontrib>MCCRACKEN, K. A</creatorcontrib><creatorcontrib>PATIL, M</creatorcontrib><creatorcontrib>PROHASKA, O. 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J</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Stimulus-activated changes in brain tissue temperature in the anesthetized rat</atitle><jtitle>Metabolic brain disease</jtitle><addtitle>Metab Brain Dis</addtitle><date>1989-12-01</date><risdate>1989</risdate><volume>4</volume><issue>4</issue><spage>225</spage><epage>237</epage><pages>225-237</pages><issn>0885-7490</issn><eissn>1573-7365</eissn><coden>MBDIEE</coden><abstract>A new thin-film, multisensor probe was used to determine tissue oxygen tension, tissue temperature, and electrical activity at two depths below the brain surface in chloral hydrate- or nitrous oxide/halothane-anesthetized rats. Brain tissue temperature at both depths was found to be lower than core temperature by 1-2 degrees C. Electrical activation, spreading depression, and pentylenetetrazol seizures all resulted in transient increases of brain tissue temperature of a few tenths degree centigrade. Vasodilation, induced by hypercapnia or hypoxia, caused a warming of brain tissue. Near-maximum oxygen metabolism, reached upon reoxygenation after severe hypoxia, was accompanied by tissue temperature rises of greater than 1 degree C. It was concluded that brain tissue temperature in the anesthetized rat is lower than core temperature due to extensive radiative and conductive heat loss to the environment through the head. Transient increases in tissue temperature during activation are caused by vasodilation and increased metabolism.</abstract><cop>New York, NY</cop><pub>Springer</pub><pmid>2601641</pmid><doi>10.1007/bf00999769</doi><tpages>13</tpages></addata></record> |
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| identifier | ISSN: 0885-7490 |
| ispartof | Metabolic brain disease, 1989-12, Vol.4 (4), p.225-237 |
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| language | eng |
| recordid | cdi_crossref_primary_10_1007_BF00999769 |
| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Anesthesia Animals Biochemistry and metabolism Biological and medical sciences Body Temperature - physiology Brain - blood supply Brain - physiopathology Central nervous system Chloral Hydrate Electric Stimulation Electroencephalography Fundamental and applied biological sciences. Psychology Halothane Hypercapnia - physiopathology Hypoxia - physiopathology Nitrous Oxide Pentylenetetrazole Rats Seizures - chemically induced Seizures - physiopathology Vasodilation Vertebrates: nervous system and sense organs |
| title | Stimulus-activated changes in brain tissue temperature in the anesthetized rat |
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