Effect of iron overload in the isolated ischemic and reperfused rat heart

It has been suggested that iron might play a pivotal role in the development of reperfusion-induced cellular injury through the activation of oxygen free radical producing reactions. The present study examined the effects of myocardial iron overload on cardiac vulnerability to ischemia and reperfusi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cardiovascular drugs and therapy 1993-08, Vol.7 (4), p.701-711
Hauptverfasser:	PUCHEU, S, COUDRAY, C, TRESALLET, N, FAVIER, A, DE LEIRIS, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Blood Pressure - drug effects Cardiology. Vascular system Catalase - metabolism Coronary heart disease Deferoxamine - pharmacology Female Freezing Glutathione Peroxidase - metabolism Heart Heart Rate - drug effects In Vitro Techniques Iron - antagonists & inhibitors Iron - pharmacokinetics Iron - toxicity Iron Chelating Agents - pharmacology L-Lactate Dehydrogenase - metabolism Medical sciences Mitochondria, Heart - drug effects Myocardial Ischemia - enzymology Myocardial Ischemia - pathology Myocardial Reperfusion Injury - enzymology Myocardial Reperfusion Injury - pathology Myocardium - enzymology Myocardium - pathology Rats Rats, Wistar Sarcomeres - drug effects Superoxide Dismutase - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!