Phase II study of amonafide in the treatment of patients with advanced squamous cell carcinoma of the head and the neck : An Illinois Cancer Center Study

Amonafide (nafidimide), a synthetic organic compound with an inhibitory effect on cellular replication, was used in a phase II study conducted by the Illinois Cancer Center in order to assess its efficacy and toxicity in advanced or recurrent squamous cell cancer of the head and neck. Eligible patie...

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Veröffentlicht in:	Investigational new drugs 1995-01, Vol.13 (3), p.249-252
Hauptverfasser:	ROSEN, F, VOKES, E. E, LAD, T, KIES, M, WADE, J. III, KILTON, L. J, BLOUGH, R, FRENCH, S, MULLANE, M, BENSON, A. B
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antineoplastic agents Antineoplastic Agents - adverse effects Antineoplastic Agents - therapeutic use Biological and medical sciences Carcinoma, Squamous Cell - drug therapy Carcinoma, Squamous Cell - secondary Chemotherapy Female Head and Neck Neoplasms - drug therapy Head and Neck Neoplasms - pathology Humans Imides - adverse effects Imides - therapeutic use Isoquinolines - adverse effects Isoquinolines - therapeutic use Male Medical sciences Middle Aged Naphthalimides Pharmacology. Drug treatments Treatment Outcome
Online-Zugang:	Volltext
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