Detection of axillary lymph node metastases in breast carcinoma by technetium-99m sestamibi breast scintigraphy, ultrasound and conventional mammography
Axillary lymph node status is important in the staging of breast carcinoma. To evaluate the accuracy of technetium-99m sestamibi breast scintigraphy in detecting metastatic axillary lymph nodes as compared with other accepted imaging modalities, we performed 99mTc-sestamibi breast scintigraphy, conv...
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| Veröffentlicht in: | European Journal of Nuclear Medicine 1996-05, Vol.23 (5), p.498-503 |
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| container_end_page | 503 |
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| container_issue | 5 |
| container_start_page | 498 |
| container_title | European Journal of Nuclear Medicine |
| container_volume | 23 |
| creator | LAM, W. W. M YANG, W. T CHAN, Y. L STEWART, I. E. T METREWELI, C KING, W |
| description | Axillary lymph node status is important in the staging of breast carcinoma. To evaluate the accuracy of technetium-99m sestamibi breast scintigraphy in detecting metastatic axillary lymph nodes as compared with other accepted imaging modalities, we performed 99mTc-sestamibi breast scintigraphy, conventional mammography and ultrasound in 36 patients with primary untreated breast carcinoma. With histopathology as the gold standard, 99mTc-sestamibi breast scintigraphy was found to yield true-positive results in 7 of 11 cases (64%) of axillary lymph node metastases and true-negative results in 18 of 20 cases (90%); it has an accuracy of 81%, a positive predictive value of 77.8% and a negative predictive value of 81.8%. |
| doi_str_mv | 10.1007/BF00833382 |
| format | Article |
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With histopathology as the gold standard, 99mTc-sestamibi breast scintigraphy was found to yield true-positive results in 7 of 11 cases (64%) of axillary lymph node metastases and true-negative results in 18 of 20 cases (90%); it has an accuracy of 81%, a positive predictive value of 77.8% and a negative predictive value of 81.8%.</description><identifier>ISSN: 0340-6997</identifier><identifier>EISSN: 1619-7089</identifier><identifier>DOI: 10.1007/BF00833382</identifier><identifier>PMID: 8698052</identifier><identifier>CODEN: EJNMD9</identifier><language>eng</language><publisher>Berlin: Springer</publisher><subject>Axilla ; Biological and medical sciences ; Breast Neoplasms - pathology ; Female ; Female genital diseases ; Gynecology. Andrology. 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With histopathology as the gold standard, 99mTc-sestamibi breast scintigraphy was found to yield true-positive results in 7 of 11 cases (64%) of axillary lymph node metastases and true-negative results in 18 of 20 cases (90%); it has an accuracy of 81%, a positive predictive value of 77.8% and a negative predictive value of 81.8%.</description><subject>Axilla</subject><subject>Biological and medical sciences</subject><subject>Breast Neoplasms - pathology</subject><subject>Female</subject><subject>Female genital diseases</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Lymph Nodes - pathology</subject><subject>Lymphatic Metastasis - diagnosis</subject><subject>Mammography</subject><subject>Medical sciences</subject><subject>Neoplasm Staging</subject><subject>Pilot Projects</subject><subject>Predictive Value of Tests</subject><subject>Sensitivity and Specificity</subject><subject>Technetium Tc 99m Sestamibi</subject><subject>Tumors</subject><subject>Ultrasonography, Mammary</subject><issn>0340-6997</issn><issn>1619-7089</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1996</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkU9P3DAQxS0EWrbApfdKPiAOFaHjOH_sY0u7gITUSzlHE8fuuortxU4Q-034uDXaBaQZjUbz09PTG0I-M7hiAO23HysAwTkX5QFZsobJogUhD8kSeAVFI2V7TD6l9A8AqorXC7IQjRRQl0vy8lNPWk02eBoMxWc7jhi3dNy6zZr6MGjq9IQpl07UetpHnTeqMCrrg0Pab2kWWHs92dkVUjqayQmd7e0bnDI62b8RN-vtJZ3HKWIKsx8o5lbBP2n_agBH6tC5sANPyZHBMemz_TwhD6tff65vi_vfN3fX3-8LxRmbCo2CQd1I1bclVrVkIBrDRN-0kqkekZVoBNcDqwbe9sZUpZCl4QaVKOtGaH5CLna6mxge52y9czYpnWPwOsypawWUrOFtBr_uQBVDSlGbbhOty2F1DLrXN3Qfb8jwl73q3Ds9vKP73PP9fH_HpHA0Eb2y6R3jUAshKv4fYKeSqg</recordid><startdate>19960501</startdate><enddate>19960501</enddate><creator>LAM, W. 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Obstetrics</topic><topic>Humans</topic><topic>Lymph Nodes - pathology</topic><topic>Lymphatic Metastasis - diagnosis</topic><topic>Mammography</topic><topic>Medical sciences</topic><topic>Neoplasm Staging</topic><topic>Pilot Projects</topic><topic>Predictive Value of Tests</topic><topic>Sensitivity and Specificity</topic><topic>Technetium Tc 99m Sestamibi</topic><topic>Tumors</topic><topic>Ultrasonography, Mammary</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>LAM, W. W. M</creatorcontrib><creatorcontrib>YANG, W. T</creatorcontrib><creatorcontrib>CHAN, Y. L</creatorcontrib><creatorcontrib>STEWART, I. E. 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T</au><au>METREWELI, C</au><au>KING, W</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Detection of axillary lymph node metastases in breast carcinoma by technetium-99m sestamibi breast scintigraphy, ultrasound and conventional mammography</atitle><jtitle>European Journal of Nuclear Medicine</jtitle><addtitle>Eur J Nucl Med</addtitle><date>1996-05-01</date><risdate>1996</risdate><volume>23</volume><issue>5</issue><spage>498</spage><epage>503</epage><pages>498-503</pages><issn>0340-6997</issn><eissn>1619-7089</eissn><coden>EJNMD9</coden><abstract>Axillary lymph node status is important in the staging of breast carcinoma. To evaluate the accuracy of technetium-99m sestamibi breast scintigraphy in detecting metastatic axillary lymph nodes as compared with other accepted imaging modalities, we performed 99mTc-sestamibi breast scintigraphy, conventional mammography and ultrasound in 36 patients with primary untreated breast carcinoma. With histopathology as the gold standard, 99mTc-sestamibi breast scintigraphy was found to yield true-positive results in 7 of 11 cases (64%) of axillary lymph node metastases and true-negative results in 18 of 20 cases (90%); it has an accuracy of 81%, a positive predictive value of 77.8% and a negative predictive value of 81.8%.</abstract><cop>Berlin</cop><pub>Springer</pub><pmid>8698052</pmid><doi>10.1007/BF00833382</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0340-6997 |
| ispartof | European Journal of Nuclear Medicine, 1996-05, Vol.23 (5), p.498-503 |
| issn | 0340-6997 1619-7089 |
| language | eng |
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| source | MEDLINE; SpringerLink Journals |
| subjects | Axilla Biological and medical sciences Breast Neoplasms - pathology Female Female genital diseases Gynecology. Andrology. Obstetrics Humans Lymph Nodes - pathology Lymphatic Metastasis - diagnosis Mammography Medical sciences Neoplasm Staging Pilot Projects Predictive Value of Tests Sensitivity and Specificity Technetium Tc 99m Sestamibi Tumors Ultrasonography, Mammary |
| title | Detection of axillary lymph node metastases in breast carcinoma by technetium-99m sestamibi breast scintigraphy, ultrasound and conventional mammography |
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