Electrocardiographic and hemodynamic effects of tocainide (W-36095) in man

Tocainide is a new antiarrhythmic drug with a chemical structure related to that of lidocaine. In the present study, healthy volunteers were investigated after infusion of tocainide 450 mg over 45 min. In nine subjects His bundle electrograms, sinus recovery time and ventricular effective refractory...

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Veröffentlicht in:	European journal of clinical pharmacology 1978-01, Vol.14 (1), p.15-19
Hauptverfasser:	Swedberg, K, Pehrson, J, Rydén, L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anilides - adverse effects Anilides - blood Anilides - pharmacology Anti-Arrhythmia Agents - adverse effects Anti-Arrhythmia Agents - blood Anti-Arrhythmia Agents - pharmacology Electrocardiography Heart Conduction System - drug effects Hemodynamics - drug effects Humans Refractory Period, Electrophysiological - drug effects Sinoatrial Node - drug effects Time Factors
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