The effects of food and dose of the oral systemic availability of itraconazole in healthy subjects

We have studied the influence of food and dose (50, 100, 200 mg) on the oral systemic availability of the broad spectrum antifungal itraconazole and the pharmacokinetics after repeated dosing of 100 mg in six healthy volunteers. The relative systemic availability of itraconazole capsules compared wi...

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Veröffentlicht in:	European journal of clinical pharmacology 1989-07, Vol.36 (4), p.423-426
Hauptverfasser:	VAN PEER, A, WOESTENBORGHS, R, HEYKANTS, J, GASPARINI, R, GAUWENBERGH, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adult Antibiotics. Antiinfectious agents. Antiparasitic agents Antifungal agents Antifungal Agents - administration & dosage Antifungal Agents - adverse effects Antifungal Agents - pharmacokinetics Biological and medical sciences Dose-Response Relationship, Drug Food Humans Itraconazole Ketoconazole - administration & dosage Ketoconazole - adverse effects Ketoconazole - analogs & derivatives Ketoconazole - pharmacokinetics Male Medical sciences Pharmacology. Drug treatments Random Allocation Reference Values
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