Muscle changes in rheumatoid arthritis. A review of the literature with a study of 100 cases
Muscle changes were studied in biopsy material obtained from 100 patients suffering from classical rheumatoid arthritis. The abnormalities consisted of denervation atrophy of type II muscle fibres, degenerative changes in the sarcoplasm including presence of nemaline rods, and changes within the int...
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Veröffentlicht in: | Virchows Archiv A Pathological Anatomy and Histology 1977-04, Vol.373 (3), p.267-278 |
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creator | Magyar, E Talerman, A Mohácsy, J Wouters, H W de Bruijn, W C |
description | Muscle changes were studied in biopsy material obtained from 100 patients suffering from classical rheumatoid arthritis. The abnormalities consisted of denervation atrophy of type II muscle fibres, degenerative changes in the sarcoplasm including presence of nemaline rods, and changes within the interstitium: namely perivascular nodular myositis, lymphocytic accumulations, different stages of vasculitis and abnormalities within the intramuscular nerves and muscle spindles. The muscles examined were always severely affected. It is considered that the simultaneous presence of these abnormalities is suggestive of rheumatoid arthritis. The importance of histochemical studies is emphasized. The literature concerning muscle changes in rheumatoid arthritis is reviewed. |
doi_str_mv | 10.1007/BF00432241 |
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The importance of histochemical studies is emphasized. The literature concerning muscle changes in rheumatoid arthritis is reviewed.</description><identifier>ISSN: 0340-1227</identifier><identifier>EISSN: 1432-2307</identifier><identifier>DOI: 10.1007/BF00432241</identifier><identifier>PMID: 140507</identifier><language>eng</language><publisher>Germany</publisher><subject>Adult ; Aged ; Arthritis, Rheumatoid - pathology ; Blood Vessels - pathology ; Connective Tissue - pathology ; Humans ; Middle Aged ; Muscle Spindles - pathology ; Muscles - blood supply ; Muscles - pathology ; Muscular Atrophy ; Myositis</subject><ispartof>Virchows Archiv A Pathological Anatomy and Histology, 1977-04, Vol.373 (3), p.267-278</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c240t-f4bbc9a6b8ecf1f748c58bcb52ee5bf0fb828a5d2792b71c0ff2ace6982eb6633</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/140507$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Magyar, E</creatorcontrib><creatorcontrib>Talerman, A</creatorcontrib><creatorcontrib>Mohácsy, J</creatorcontrib><creatorcontrib>Wouters, H W</creatorcontrib><creatorcontrib>de Bruijn, W C</creatorcontrib><title>Muscle changes in rheumatoid arthritis. 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The literature concerning muscle changes in rheumatoid arthritis is reviewed.</description><subject>Adult</subject><subject>Aged</subject><subject>Arthritis, Rheumatoid - pathology</subject><subject>Blood Vessels - pathology</subject><subject>Connective Tissue - pathology</subject><subject>Humans</subject><subject>Middle Aged</subject><subject>Muscle Spindles - pathology</subject><subject>Muscles - blood supply</subject><subject>Muscles - pathology</subject><subject>Muscular Atrophy</subject><subject>Myositis</subject><issn>0340-1227</issn><issn>1432-2307</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1977</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkDtPwzAUhS3EqxQWZgZPDEgp187LGUtFAamIBTakyHauiVHSFNuh6r8npZU63SPdT0dHHyHXDCYMIL9_mAMkMecJOyIjNqSIx5AfkxHECUSM8_ycXHj_DZCmTMRn5JQlkEI-Ip-vvdcNUl3L5Rd6apfU1di3MnS2otKF2tlg_YROqcNfi2vaGRpqpI0N6GToHdK1DTWV1Ie-2mzfwySqpUd_SU6MbDxe7e-YfMwf32fP0eLt6WU2XUSaJxAikyilC5kpgdowkydCp0JplXLEVBkwSnAh04rnBVc502AMlxqzQnBUWRbHY3K761257qdHH8rWeo1NI5fY9b4UcQECBB_Aux2oXee9Q1OunG2l25QMyq3J8mBygG_2rb1qsTqg_-riPz7FbcU</recordid><startdate>19770406</startdate><enddate>19770406</enddate><creator>Magyar, E</creator><creator>Talerman, A</creator><creator>Mohácsy, J</creator><creator>Wouters, H W</creator><creator>de Bruijn, W C</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19770406</creationdate><title>Muscle changes in rheumatoid arthritis. 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A review of the literature with a study of 100 cases</atitle><jtitle>Virchows Archiv A Pathological Anatomy and Histology</jtitle><addtitle>Virchows Arch A Pathol Anat Histol</addtitle><date>1977-04-06</date><risdate>1977</risdate><volume>373</volume><issue>3</issue><spage>267</spage><epage>278</epage><pages>267-278</pages><issn>0340-1227</issn><eissn>1432-2307</eissn><abstract>Muscle changes were studied in biopsy material obtained from 100 patients suffering from classical rheumatoid arthritis. The abnormalities consisted of denervation atrophy of type II muscle fibres, degenerative changes in the sarcoplasm including presence of nemaline rods, and changes within the interstitium: namely perivascular nodular myositis, lymphocytic accumulations, different stages of vasculitis and abnormalities within the intramuscular nerves and muscle spindles. The muscles examined were always severely affected. It is considered that the simultaneous presence of these abnormalities is suggestive of rheumatoid arthritis. The importance of histochemical studies is emphasized. The literature concerning muscle changes in rheumatoid arthritis is reviewed.</abstract><cop>Germany</cop><pmid>140507</pmid><doi>10.1007/BF00432241</doi><tpages>12</tpages></addata></record> |
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subjects | Adult Aged Arthritis, Rheumatoid - pathology Blood Vessels - pathology Connective Tissue - pathology Humans Middle Aged Muscle Spindles - pathology Muscles - blood supply Muscles - pathology Muscular Atrophy Myositis |
title | Muscle changes in rheumatoid arthritis. A review of the literature with a study of 100 cases |
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