Chronic lathyrism and atheromatosis in the rat. Study of the V.L.D.L. and plasma and arterial wall lipids
Temporary chronic administration of Beta-amino-propionitrile (B.A.P.N.) produced morphological and biochemical changes of the aortic wall of rat as well as abnormalities of the plasma lipid levels. A hyperlipidic diet resulted in the blood plasma lipid abnormalities as B.A.P.N. intoxication. Nine we...
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| Veröffentlicht in: | Virchows Archiv A Pathological Anatomy and Histology 1978-10, Vol.380 (2), p.107-117 |
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| container_end_page | 117 |
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| container_issue | 2 |
| container_start_page | 107 |
| container_title | Virchows Archiv A Pathological Anatomy and Histology |
| container_volume | 380 |
| creator | Bouissou, H Thiers, J C Douste-Blazy, L Pieraggi, M T Julian, M |
| description | Temporary chronic administration of Beta-amino-propionitrile (B.A.P.N.) produced morphological and biochemical changes of the aortic wall of rat as well as abnormalities of the plasma lipid levels. A hyperlipidic diet resulted in the blood plasma lipid abnormalities as B.A.P.N. intoxication. Nine weeks of B.A.P.N. followed by 42 weeks of a hyperlipidic diet increased the aortic cholesterol level and induced an atheroma. The diet alone produced only an endothelial lipid overload. The structure of arterial wall played the decisive role in atherogenesis. |
| doi_str_mv | 10.1007/BF00430617 |
| format | Article |
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The structure of arterial wall played the decisive role in atherogenesis.</description><subject>Aminopropionitrile</subject><subject>Animals</subject><subject>Arteries - analysis</subject><subject>Arteriosclerosis - blood</subject><subject>Arteriosclerosis - etiology</subject><subject>Cholesterol - blood</subject><subject>Chronic Disease</subject><subject>Lathyrism - blood</subject><subject>Lathyrism - complications</subject><subject>Lipids - analysis</subject><subject>Lipids - blood</subject><subject>Lipoproteins, VLDL - blood</subject><subject>Male</subject><subject>Rats</subject><issn>0340-1227</issn><issn>1432-2307</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1978</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkEtPwzAQhC3EqxQunDn4jJSw60fdHKFQQKrEgcc1cmJbNXKayA5C_fekDYLDajWrb1aaIeQSIUcAdXO3BBAcZqgOyAQFZxnjoA7JBLiADBlTp-QspU8AKXHOT8gxQ1FwNSF-sY7txtc06H69jT41VG8MHYSNbaP7NvlE_YYOmkbd5_S1_zJb2rr95SNf5ffD7D1d0KnRoz32Nnod6LcOgQbfeZPOyZHTIdmL3z0l78uHt8VTtnp5fF7crrKaCeizSksEhq6aW7Rzw1ghKjmTyrGiUlyIwtUGJXC5S6tnBiQo7gohbYVgZcGn5Hr8W8c2pWhd2UXf6LgtEcpdW-V_WwN8NcLdV9VY84eO9fAfvSliig</recordid><startdate>19781026</startdate><enddate>19781026</enddate><creator>Bouissou, H</creator><creator>Thiers, J C</creator><creator>Douste-Blazy, L</creator><creator>Pieraggi, M T</creator><creator>Julian, M</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>19781026</creationdate><title>Chronic lathyrism and atheromatosis in the rat. 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| fulltext | fulltext |
| identifier | ISSN: 0340-1227 |
| ispartof | Virchows Archiv A Pathological Anatomy and Histology, 1978-10, Vol.380 (2), p.107-117 |
| issn | 0340-1227 1432-2307 |
| language | eng |
| recordid | cdi_crossref_primary_10_1007_BF00430617 |
| source | MEDLINE; Springer Nature - Complete Springer Journals |
| subjects | Aminopropionitrile Animals Arteries - analysis Arteriosclerosis - blood Arteriosclerosis - etiology Cholesterol - blood Chronic Disease Lathyrism - blood Lathyrism - complications Lipids - analysis Lipids - blood Lipoproteins, VLDL - blood Male Rats |
| title | Chronic lathyrism and atheromatosis in the rat. Study of the V.L.D.L. and plasma and arterial wall lipids |
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