A genetic analysis of the response to morphine in mice: analgesia and running

Two progenitor strains, BALB/cBy and C57BL/6By, their reciprocal F1 hybrids, and seven of their recombinant-inbred derived lines were used to examine the genetic basis of the response to thermal pain, and morphine analgesia at doses of 2.5, 5.0 and 10.0mg/kg. Both the latency of response to thermal...

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Veröffentlicht in:	Psychopharmacologia 1975-01, Vol.42 (3), p.249-254
Hauptverfasser:	Shuster, L, Webster, G W, Yu, G, Eleftheriou, B E
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesia Analysis of Variance Animals Crosses, Genetic Genotype Hybridization, Genetic Male Mice Mice, Inbred BALB C - physiology Mice, Inbred C57BL - physiology Mice, Inbred Strains - physiology Morphine - pharmacology Motor Activity - drug effects Pharmacogenetics Reaction Time - drug effects Recombination, Genetic Species Specificity
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