Inhibition of benzo(a)pyrene carcinogenesis in rats with vitamin C

The s.c. infection of 10 mg benzo(a)pyrene dissolved in 1 ml tricaprylin induced in Wistar rats local malignant tumors, such as fibrosarcoma, rhabdomyosarcoma, and polymorph cell sarcoma. The growth of the tumors was relatively rapid, reaching weights of 140-155 g before rats died 142-168 days after...

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Veröffentlicht in:	Journal of cancer research and clinical oncology 1980-01, Vol.97 (1), p.91-96
Hauptverfasser:	Kallistratos, G, Fasske, E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Ascorbic Acid - pharmacology Benzopyrenes - toxicity Dose-Response Relationship, Drug Fibrosarcoma - chemically induced Neoplasms, Experimental - chemically induced Neoplasms, Experimental - prevention & control Rats Rhabdomyosarcoma - chemically induced Sarcoma, Experimental - chemically induced
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