Preliminary findings on calmodulin-stimulated Ca2+-ATPase of erythrocyte ghosts in psychotic patients

Kinetic properties of the calmodulin-stimulated erythrocyte ghost Ca2+-ATPase seem to be altered in some sub-groups of affective and schizophrenic psychoses. The sub-group of affective disorders concerned mostly unipolar manic and bipolar psychoses with predominantly manic episodes. In the correspon...

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Veröffentlicht in:European Archives of Psychiatry and Neurological Sciences 1985-01, Vol.235 (1), p.57-59
Hauptverfasser: KLUGE, H, KÜHNE, G. E
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KÜHNE, G. E
description Kinetic properties of the calmodulin-stimulated erythrocyte ghost Ca2+-ATPase seem to be altered in some sub-groups of affective and schizophrenic psychoses. The sub-group of affective disorders concerned mostly unipolar manic and bipolar psychoses with predominantly manic episodes. In the corresponding cases from schizophrenics hyper- and parakinetic basic syndromes were predominantly diagnosed. An evaluation of our preliminary results was undertaken in connection with our biochemical hypothesis on possible alterations in the regulation of Ca2+ concentrations and Ca2+-calmodulin-mediated processes under certain psychotic conditions.
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subjects Adult and adolescent clinical studies
Biological and medical sciences
Bipolar Disorder - enzymology
Calcium - blood
Calcium-Transporting ATPases - blood
Calmodulin - blood
Depressive Disorder - enzymology
Erythrocyte Membrane - enzymology
Humans
Kinetics
Medical sciences
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Psychoses
Psychotic Disorders - enzymology
Schizophrenia - enzymology
title Preliminary findings on calmodulin-stimulated Ca2+-ATPase of erythrocyte ghosts in psychotic patients
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