Aristolochic acid is mutagenic and recombinogenic in Drosophila genotoxicity tests

Aristolochic acid (AA) has been tested for genotoxic activity in three different assays with Drosophila melanogaster (i-iii). AA induced sex-linked recessive lethals (i) and chromosome losses (ii) in male germ cells. In a newly developed fast assay with somatic cells of larvae (iii), AA induced muta...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Archives of toxicology 1985, Vol.56 (3), p.158-166
Hauptverfasser:	Frei, H, Wurgler, F.E, Juon, H, Hall, C.B, Graf, U
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents - toxicity aristolochia clematitis Aristolochic Acids Biological and medical sciences Chemical mutagenesis Doxorubicin - toxicity Drosophila melanogaster Female Genes, Lethal - drug effects Genes, Recessive - drug effects Genotype Male Medical sciences medicinal plants mutagenicity Mutagenicity Tests - methods Mutagens Phenanthrenes - toxicity plant extracts Recombination, Genetic - drug effects Sex Chromosomes - drug effects Toxicology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!