Metformin for obese, insulin-treated diabetic patients : improvement in glycaemic control and reduction of metabolic risk factors

The efficacy and safety of metformin in the treatment of obese, non-insulin-dependent, diabetic subjects poorly controlled by insulin after secondary failure to respond to sulphonylureas has been investigated. Fifty insulin-treated, obese diabetics participated in this prospective, randomised double...

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Veröffentlicht in:	European journal of clinical pharmacology 1993-03, Vol.44 (2), p.107-112
Hauptverfasser:	GIUGLIANO, D, QUATRARO, A, CONSOLI, G, MINEI, A, CERIELLO, A, DE ROSA, N, D'ONOFRIO, F
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Blood Glucose - metabolism Blood Pressure - drug effects C-Peptide - blood Diabetes Mellitus - drug therapy Diabetes Mellitus - metabolism Diabetes Mellitus, Type 2 - drug therapy Diabetes Mellitus, Type 2 - metabolism Double-Blind Method Female General and cellular metabolism. Vitamins Glucagon - pharmacology Glycated Hemoglobin A - metabolism Homeostasis - physiology Humans Islets of Langerhans - drug effects Islets of Langerhans - metabolism Lipids - blood Male Medical sciences Metformin - adverse effects Metformin - therapeutic use Middle Aged Obesity Pharmacology. Drug treatments Prospective Studies Risk Factors Single-Blind Method
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