Adenosine and deoxyadenosine toxicity in colony assay systems for human T-lymphocytes, B-lymphocytes, and granulocytes

Adenosine and deoxyadenosine toxicity was examined in colony assay systems for human T lymphocytes, B lymphocytes, and granulocytes. In the absence of deoxycoformycin, an adenosine deaminase inhibitor, no growth inhibition was observed in the three systems with concentrations of adenosine or deoxyad...

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Veröffentlicht in:	Cancer chemotherapy and pharmacology 1982, Vol.9 (1), p.49-52
Hauptverfasser:	Brox, L W, Pollock, E, Belch, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine - toxicity B-Lymphocytes - drug effects Bone Marrow Cells Cell Survival - drug effects Coformycin - analogs & derivatives Coformycin - pharmacology Colony-Forming Units Assay Deoxyadenosines - toxicity Granulocytes - drug effects Humans Leukocytes - drug effects Pentostatin T-Lymphocytes - drug effects
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