Iodine 131 labelled ioglycamic acid (Biligram) for scintiscanning in hepatobiliary disorders
Iodine-131 labelled Biligram has been evaluated as a radiopharmaceutical for dynamic scintiscanning of the liver and biliary tract. In 10 normal subjects there was good visualisation of the liver and gallbladder. In 18 patients 131I Biligram was found to be unsatifactory for differentiating parenchy...
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| Veröffentlicht in: | European Journal Of Nuclear Medicine 1979-02, Vol.4 (1), p.7-11 |
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| container_title | European Journal Of Nuclear Medicine |
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| creator | Blackwell, J N Finlayson, N D McLoughlin, G P Sumerling, M D Tothill, P |
| description | Iodine-131 labelled Biligram has been evaluated as a radiopharmaceutical for dynamic scintiscanning of the liver and biliary tract. In 10 normal subjects there was good visualisation of the liver and gallbladder. In 18 patients 131I Biligram was found to be unsatifactory for differentiating parenchymal liver disease from biliary tract obstruction owing to inability to demonstrate the gallbladder when liver function was more than mildly deranged. Quantitative analyses of blood clearance and hepatic activity curves for 131I Biligram were not clinically helpful. Urinary excretion of 131I Biligram increased with the degree of hepatic dysfunction. |
| doi_str_mv | 10.1007/BF00257562 |
| format | Article |
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In 10 normal subjects there was good visualisation of the liver and gallbladder. In 18 patients 131I Biligram was found to be unsatifactory for differentiating parenchymal liver disease from biliary tract obstruction owing to inability to demonstrate the gallbladder when liver function was more than mildly deranged. Quantitative analyses of blood clearance and hepatic activity curves for 131I Biligram were not clinically helpful. 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In 10 normal subjects there was good visualisation of the liver and gallbladder. In 18 patients 131I Biligram was found to be unsatifactory for differentiating parenchymal liver disease from biliary tract obstruction owing to inability to demonstrate the gallbladder when liver function was more than mildly deranged. Quantitative analyses of blood clearance and hepatic activity curves for 131I Biligram were not clinically helpful. Urinary excretion of 131I Biligram increased with the degree of hepatic dysfunction.</description><subject>Biliary Tract Diseases - diagnostic imaging</subject><subject>Diagnosis, Differential</subject><subject>Half-Life</subject><subject>Humans</subject><subject>Iodine Radioisotopes - metabolism</subject><subject>Iodobenzoates</subject><subject>Ioglycamic Acid - metabolism</subject><subject>Kinetics</subject><subject>Liver Diseases - diagnostic imaging</subject><subject>Liver Diseases - physiopathology</subject><subject>Radionuclide Imaging</subject><issn>0340-6997</issn><issn>1619-7089</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1979</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkDtPwzAYRS3EqxQWZgZPCJACfjseaUWhUiUW2JAix_5ajJK42OnQf09QK5jucnR170HokpJ7Soh-mMwIYVJLxQ7QiCpqCk1Kc4hGhAtSKGP0KTrL-YsQIgSXJ-hYGMOYGaGPefShA0w5xY2toWnA4xBXzdbZNjhsXfD4ZhKasEq2vcXLmHB2oetDdrbrQrfCocOfsLZ9rAfKpi32IcfkIeVzdLS0TYaLfY7R--zpbfpSLF6f59PHReGolH1hylJZoaUXFgCoMaqkXlGpuNW1lNaVS8_AS0cF8JpD6VltOTBBSlYrCXyMrne96xS_N5D7qh3mDV9sB3GTKy20ZiVlA3i3A12KOSdYVusU2mFzRUn1a7L6NznAV_vWTd2C_0N36vgPE_NtnA</recordid><startdate>19790201</startdate><enddate>19790201</enddate><creator>Blackwell, J N</creator><creator>Finlayson, N D</creator><creator>McLoughlin, G P</creator><creator>Sumerling, M D</creator><creator>Tothill, P</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19790201</creationdate><title>Iodine 131 labelled ioglycamic acid (Biligram) for scintiscanning in hepatobiliary disorders</title><author>Blackwell, J N ; Finlayson, N D ; McLoughlin, G P ; Sumerling, M D ; Tothill, P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c155t-9886a475d4aeee199681d61563a7b55ac8fd2ed5c14e3b3e8d2ba3e24082b65e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1979</creationdate><topic>Biliary Tract Diseases - diagnostic imaging</topic><topic>Diagnosis, Differential</topic><topic>Half-Life</topic><topic>Humans</topic><topic>Iodine Radioisotopes - metabolism</topic><topic>Iodobenzoates</topic><topic>Ioglycamic Acid - metabolism</topic><topic>Kinetics</topic><topic>Liver Diseases - diagnostic imaging</topic><topic>Liver Diseases - physiopathology</topic><topic>Radionuclide Imaging</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Blackwell, J N</creatorcontrib><creatorcontrib>Finlayson, N D</creatorcontrib><creatorcontrib>McLoughlin, G P</creatorcontrib><creatorcontrib>Sumerling, M D</creatorcontrib><creatorcontrib>Tothill, P</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European Journal Of Nuclear Medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Blackwell, J N</au><au>Finlayson, N D</au><au>McLoughlin, G P</au><au>Sumerling, M D</au><au>Tothill, P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Iodine 131 labelled ioglycamic acid (Biligram) for scintiscanning in hepatobiliary disorders</atitle><jtitle>European Journal Of Nuclear Medicine</jtitle><addtitle>Eur J Nucl Med</addtitle><date>1979-02-01</date><risdate>1979</risdate><volume>4</volume><issue>1</issue><spage>7</spage><epage>11</epage><pages>7-11</pages><issn>0340-6997</issn><eissn>1619-7089</eissn><abstract>Iodine-131 labelled Biligram has been evaluated as a radiopharmaceutical for dynamic scintiscanning of the liver and biliary tract. 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| fulltext | fulltext |
| identifier | ISSN: 0340-6997 |
| ispartof | European Journal Of Nuclear Medicine, 1979-02, Vol.4 (1), p.7-11 |
| issn | 0340-6997 1619-7089 |
| language | eng |
| recordid | cdi_crossref_primary_10_1007_BF00257562 |
| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Biliary Tract Diseases - diagnostic imaging Diagnosis, Differential Half-Life Humans Iodine Radioisotopes - metabolism Iodobenzoates Ioglycamic Acid - metabolism Kinetics Liver Diseases - diagnostic imaging Liver Diseases - physiopathology Radionuclide Imaging |
| title | Iodine 131 labelled ioglycamic acid (Biligram) for scintiscanning in hepatobiliary disorders |
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