cis-platinum and etoposide combination chemotherapy of advanced non-oat cell bronchogenic carcinoma
From December 1981 to November 1982, a consecutive series of 37 patients with advanced non-oat cell bronchogenic carcinoma were treated with cis-platinum and etoposide in doses of 20 mg/m2 and 75 mg/m2, respectively, for 5 consecutive days every 3 weeks. Among the 33 evaluable patients, one complete...
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| Veröffentlicht in: | Cancer chemotherapy and pharmacology 1983-01, Vol.11 (1), p.35 |
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| container_title | Cancer chemotherapy and pharmacology |
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| creator | Veronesi, A Zagonel, V Santarossa, M Tirelli, U Galligioni, E Trovo', M G Tumolo, S Grigoletto, E |
| description | From December 1981 to November 1982, a consecutive series of 37 patients with advanced non-oat cell bronchogenic carcinoma were treated with cis-platinum and etoposide in doses of 20 mg/m2 and 75 mg/m2, respectively, for 5 consecutive days every 3 weeks. Among the 33 evaluable patients, one complete response, 11 partial responses, five minor responses, seven unchanged states, and nine cases of progression were noted. Median duration of response was 30+ weeks. Toxicity was significant, but no treatment-related deaths were encountered. Combined cis-platinum and etoposide can provide significant palliation in approximately one-third of patients with the doses and schedule used. |
| doi_str_mv | 10.1007/BF00257414 |
| format | Article |
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Among the 33 evaluable patients, one complete response, 11 partial responses, five minor responses, seven unchanged states, and nine cases of progression were noted. Median duration of response was 30+ weeks. Toxicity was significant, but no treatment-related deaths were encountered. Combined cis-platinum and etoposide can provide significant palliation in approximately one-third of patients with the doses and schedule used.</description><identifier>ISSN: 0344-5704</identifier><identifier>EISSN: 1432-0843</identifier><identifier>DOI: 10.1007/BF00257414</identifier><identifier>PMID: 6683999</identifier><language>eng</language><publisher>Germany</publisher><subject>Adult ; Aged ; Carcinoma, Bronchogenic - drug therapy ; Carcinoma, Bronchogenic - radiotherapy ; Cisplatin - therapeutic use ; Drug Therapy, Combination ; Etoposide - therapeutic use ; Female ; Humans ; Lung Neoplasms - drug therapy ; Lung Neoplasms - radiotherapy ; Male ; Middle Aged ; Podophyllotoxin - analogs & derivatives</subject><ispartof>Cancer chemotherapy and pharmacology, 1983-01, Vol.11 (1), p.35</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c282t-856a8e0296117d31028f3b84c176be57b8fada3be364f6579c883b2a91f7e88c3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/6683999$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Veronesi, A</creatorcontrib><creatorcontrib>Zagonel, V</creatorcontrib><creatorcontrib>Santarossa, M</creatorcontrib><creatorcontrib>Tirelli, U</creatorcontrib><creatorcontrib>Galligioni, E</creatorcontrib><creatorcontrib>Trovo', M G</creatorcontrib><creatorcontrib>Tumolo, S</creatorcontrib><creatorcontrib>Grigoletto, E</creatorcontrib><title>cis-platinum and etoposide combination chemotherapy of advanced non-oat cell bronchogenic carcinoma</title><title>Cancer chemotherapy and pharmacology</title><addtitle>Cancer Chemother Pharmacol</addtitle><description>From December 1981 to November 1982, a consecutive series of 37 patients with advanced non-oat cell bronchogenic carcinoma were treated with cis-platinum and etoposide in doses of 20 mg/m2 and 75 mg/m2, respectively, for 5 consecutive days every 3 weeks. Among the 33 evaluable patients, one complete response, 11 partial responses, five minor responses, seven unchanged states, and nine cases of progression were noted. Median duration of response was 30+ weeks. Toxicity was significant, but no treatment-related deaths were encountered. Combined cis-platinum and etoposide can provide significant palliation in approximately one-third of patients with the doses and schedule used.</description><subject>Adult</subject><subject>Aged</subject><subject>Carcinoma, Bronchogenic - drug therapy</subject><subject>Carcinoma, Bronchogenic - radiotherapy</subject><subject>Cisplatin - therapeutic use</subject><subject>Drug Therapy, Combination</subject><subject>Etoposide - therapeutic use</subject><subject>Female</subject><subject>Humans</subject><subject>Lung Neoplasms - drug therapy</subject><subject>Lung Neoplasms - radiotherapy</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Podophyllotoxin - analogs & derivatives</subject><issn>0344-5704</issn><issn>1432-0843</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1983</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkM9LwzAYhoMoc04v3oWchWh-NUmPOpwKAy96Ll--pi7SJqXthP33Tjb09B7eh-fwEHIt-J3g3N4_rjiXhdVCn5C50Eoy7rQ6JXOutGaF5fqcXIzjF-dcC6VmZGaMU2VZzgliHFnfwhTTtqOQahqm3Ocx1oFi7nxM-ysnipvQ5WkTBuh3NDcU6m9IGGqacmIZJoqhbakfcsJN_gwpIkUYMKbcwSU5a6Adw9VxF-Rj9fS-fGHrt-fX5cOaoXRyYq4w4AKXpRHC1kpw6RrlnUZhjQ-F9a6BGpQPyujGFLZE55SXUIrGBudQLcjtwYtDHschNFU_xA6GXSV49Ruq-g-1h28OcL_1Xaj_0GMZ9QMitGQZ</recordid><startdate>19830101</startdate><enddate>19830101</enddate><creator>Veronesi, A</creator><creator>Zagonel, V</creator><creator>Santarossa, M</creator><creator>Tirelli, U</creator><creator>Galligioni, E</creator><creator>Trovo', M G</creator><creator>Tumolo, S</creator><creator>Grigoletto, E</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>19830101</creationdate><title>cis-platinum and etoposide combination chemotherapy of advanced non-oat cell bronchogenic carcinoma</title><author>Veronesi, A ; Zagonel, V ; Santarossa, M ; Tirelli, U ; Galligioni, E ; Trovo', M G ; Tumolo, S ; Grigoletto, E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c282t-856a8e0296117d31028f3b84c176be57b8fada3be364f6579c883b2a91f7e88c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1983</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Carcinoma, Bronchogenic - drug therapy</topic><topic>Carcinoma, Bronchogenic - radiotherapy</topic><topic>Cisplatin - therapeutic use</topic><topic>Drug Therapy, Combination</topic><topic>Etoposide - therapeutic use</topic><topic>Female</topic><topic>Humans</topic><topic>Lung Neoplasms - drug therapy</topic><topic>Lung Neoplasms - radiotherapy</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Podophyllotoxin - analogs & derivatives</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Veronesi, A</creatorcontrib><creatorcontrib>Zagonel, V</creatorcontrib><creatorcontrib>Santarossa, M</creatorcontrib><creatorcontrib>Tirelli, U</creatorcontrib><creatorcontrib>Galligioni, E</creatorcontrib><creatorcontrib>Trovo', M G</creatorcontrib><creatorcontrib>Tumolo, S</creatorcontrib><creatorcontrib>Grigoletto, E</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Cancer chemotherapy and pharmacology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Veronesi, A</au><au>Zagonel, V</au><au>Santarossa, M</au><au>Tirelli, U</au><au>Galligioni, E</au><au>Trovo', M G</au><au>Tumolo, S</au><au>Grigoletto, E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>cis-platinum and etoposide combination chemotherapy of advanced non-oat cell bronchogenic carcinoma</atitle><jtitle>Cancer chemotherapy and pharmacology</jtitle><addtitle>Cancer Chemother Pharmacol</addtitle><date>1983-01-01</date><risdate>1983</risdate><volume>11</volume><issue>1</issue><spage>35</spage><pages>35-</pages><issn>0344-5704</issn><eissn>1432-0843</eissn><abstract>From December 1981 to November 1982, a consecutive series of 37 patients with advanced non-oat cell bronchogenic carcinoma were treated with cis-platinum and etoposide in doses of 20 mg/m2 and 75 mg/m2, respectively, for 5 consecutive days every 3 weeks. 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| fulltext | fulltext |
| identifier | ISSN: 0344-5704 |
| ispartof | Cancer chemotherapy and pharmacology, 1983-01, Vol.11 (1), p.35 |
| issn | 0344-5704 1432-0843 |
| language | eng |
| recordid | cdi_crossref_primary_10_1007_BF00257414 |
| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Adult Aged Carcinoma, Bronchogenic - drug therapy Carcinoma, Bronchogenic - radiotherapy Cisplatin - therapeutic use Drug Therapy, Combination Etoposide - therapeutic use Female Humans Lung Neoplasms - drug therapy Lung Neoplasms - radiotherapy Male Middle Aged Podophyllotoxin - analogs & derivatives |
| title | cis-platinum and etoposide combination chemotherapy of advanced non-oat cell bronchogenic carcinoma |
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