Human pharmacokinetics of esorubicin (4'-deoxydoxorubicin)

The pharmacokinetics of esorubicin, a new anthracycline antibiotic, was investigated in conjunction with a phase I clinical trial. The drug was administered to 12 patients as an intravenous bolus at a dose of 20 to 40 mg/m2. All patients had normal renal and hepatic functions and no third space flui...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Investigational new drugs 1985-01, Vol.3 (4), p.361-368
Hauptverfasser:	Dodion, P, Davis, T A, Rozencweig, M, Crespeigne, N, Kenis, Y, Bachur, N R
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - adverse effects Antineoplastic Agents - metabolism Bone Marrow - drug effects Doxorubicin - adverse effects Doxorubicin - analogs & derivatives Doxorubicin - metabolism Humans Kinetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!