Interaction between aflatoxin B1 and oxytetracycline in isolated rat hepatocytes

Isolated rat hepatocytes were used as an in vitro model to investigate a possible interaction between oxytetracycline (OXT) and aflatoxin B1 (AFB1). LDH leakage, RNA and protein synthesis and glycogen accumulation were measured in the presence of both drugs, either separately or in combination. The...

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Veröffentlicht in:	Cell biology and toxicology 1990-10, Vol.6 (4), p.339-351
Hauptverfasser:	Blaude, M N, Goethals, F M, Ansay, M A, Roberfroid, M B
Format:	Artikel
Sprache:	eng
Schlagworte:	Aflatoxin B1 Aflatoxins - administration & dosage Aflatoxins - antagonists & inhibitors Aflatoxins - toxicity Animals Drug Interactions In Vitro Techniques Liver - drug effects Liver - metabolism Liver Glycogen - metabolism Male Oxytetracycline - administration & dosage Oxytetracycline - pharmacology Protein Biosynthesis Rats Rats, Inbred Strains RNA - biosynthesis
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