Chronology of Genetic Changes in thevpu, env,andnefGenes of Chimeric Simian–Human Immunodeficiency Virus (Strain HXB2) during Acquisition of Virulence for Pig-Tailed Macaques

Recently, we developed a highly pathogenic variant of simian–human immunodeficiency virus, SHIV-4 (containing thetat, rev, vpu,andenvof the HXB2 strain of HIV-1 in a genetic background of SIVmac239), through a series of four bone marrow-bone marrow passages—first in rhesus monkeys and then in pig-ta...

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Veröffentlicht in:	Virology (New York, N.Y.) N.Y.), 1998-09, Vol.248 (2), p.275-283
Hauptverfasser:	McCormick-Davis, Coleen, Zhao, Ling-jun, Mukherjee, Sampa, Leung, Kevin, Sheffer, Darlene, Joag, Sanjay V., Narayan, Opendra, Stephens, Edward B.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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