Mutations in Conserved Domain I of the Sendai Virus L Polymerase Protein Uncouple Transcription and Replication

To begin to map functional domains of the Sendai P-L RNA polymerase complex we wanted to characterize the P binding site on the Sendai L protein. Analysis ofin vitroandin vivoP-L polymerase complex formation with carboxyl-truncations of the L protein showed that the N-terminal half of the protein wa...

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