Enhancement of the Stress Response by Low Concentrations of Arsenite in Arsenite-Pretreated Reuber H35 Hepatoma Cells

The present study is aimed at determining whether the induction of heat-shock protein (hsp) synthesis, heat-shock mRNAs, and tolerance development after arsenite application has been sensitized to low concentrations of arsenite in Reuber H35 rat hepatoma cells. Using a step-down arsenite treatment,...

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Veröffentlicht in:	Toxicology and applied pharmacology 1995-05, Vol.132 (1), p.146-155
Hauptverfasser:	Ovelgonne, H.H., Wiegant, F.A.C., Souren, J.E.M., Vanrijn, H., Vanwijk, R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arsenites - administration & dosage Arsenites - toxicity Biological and medical sciences Blotting, Northern Cell Survival - drug effects Chemical and industrial products toxicology. Toxic occupational diseases Electrophoresis, Polyacrylamide Gel Heat-Shock Proteins - biosynthesis Heat-Shock Proteins - drug effects Liver Neoplasms, Experimental Medical sciences Metals and various inorganic compounds RNA, Messenger - biosynthesis Toxicology Tumor Cells, Cultured
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