The Mammalian Flavin-Containing Monooxygenases: Molecular Characterization and Regulation of Expression

The flavin-containing monooxygenase (FMO) has been characterized in several mammalian species, including human. The FMO forms a stable NADP(H)− and oxygen-dependent 4α-hydroperoxy flavin enzyme intermediate in the absence of an oxygenatable substrate. As such, substrate specificity appears to be con...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Toxicology and applied pharmacology 1994-03, Vol.125 (1), p.1-6
Hauptverfasser:	Hines, R.N., Cashman, J.R., Philpot, R.M., Williams, D.E., Ziegler, D.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Animals Biological and medical sciences Enzymes and enzyme inhibitors Flavins - metabolism Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Enzymologic Humans Oxidoreductases Oxygenases - biosynthesis Oxygenases - chemistry Oxygenases - genetics Oxygenases - metabolism Species Specificity Stereoisomerism Substrate Specificity Xenobiotics - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!