Cellular memory of transcriptional states by Polycomb-group proteins

The Polycomb–group constitutes an important, widely conserved group of transcriptional repressors best known for their function in stably maintaining the inactive expression patterns of key developmental regulators, including homeotic genes. Together with the counteracting trithorax–group proteins,...

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Veröffentlicht in:	Seminars in cell & developmental biology 1999-04, Vol.10 (2), p.227-235
Hauptverfasser:	Jacobs, Jacqueline J.L., van Lohuizen, Maarten
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Division cellular memory, chromatin, homeotic transformations, Polycomb-group, proliferation defects Chromatin - genetics Chromatin - ultrastructure DNA-Binding Proteins - physiology Drosophila melanogaster - genetics Drosophila melanogaster - metabolism Drosophila Proteins Embryonic and Fetal Development - genetics Female Gene Expression Regulation, Developmental - physiology Genes, Homeobox Genes, Insect Insect Proteins - physiology Male Mice Models, Genetic Multigene Family Phenotype Polycomb Repressive Complex 1 Polycomb-Group Proteins Repressor Proteins - physiology Transcription Factors Transcription, Genetic - physiology
Online-Zugang:	Volltext
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