Mutational and Structural Analysis of the RNA Binding Site for Escherichia coli Ribosomal Protein S7

Ribosomal protein S7 binds to a small RNA fragment of about 100 nucleotides within the lower half of the 3′ major domain of E. coli 16 S rRNA. This fragment (D3M) comprises two large internal loops, A and B, connected by helix 29, a six-base-pair helix containing a G·U pair. Two hairpins with non-ca...

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Veröffentlicht in:	Journal of molecular biology 1994-11, Vol.244 (1), p.74-85
Hauptverfasser:	Dragon, François, Payant, Catherine, Brakier-Gingras, Léa
Format:	Artikel
Sprache:	eng
Schlagworte:	16 S ribosomal RNA Base Sequence Binding Sites - genetics DNA Mutational Analysis Escherichia coli - genetics Escherichia coli - metabolism Molecular Probes Molecular Sequence Data Nucleic Acid Conformation Protein Binding ribosomal protein S7 Ribosomal Proteins - metabolism RNA - chemistry RNA - metabolism RNA, Bacterial - chemistry RNA, Bacterial - genetics RNA, Bacterial - metabolism RNA, Ribosomal, 16S - chemistry RNA, Ribosomal, 16S - genetics RNA, Ribosomal, 16S - metabolism RNA-protein interactions site-directed mutagenesis Structure-Activity Relationship
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