Leishmania major:Differential Resistance to Infection in C57BL/6 (High Interferon-α/β) and Congenic B6.C-H-28c(Low Interferon-α/β) Mice

In murine cutaneous leishmaniasis caused byLeishmania major(Lm), resistance often associates with the outgrowth ofLm-specific Th1 cells. Parasites are eliminated by Th1-mediated activation of infected macrophages (MØ) which destroyLmby producing toxic nitrogen and oxygen radicals. The cytokine IFN-α...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Experimental parasitology 1996-11, Vol.84 (2), p.136-143
Hauptverfasser:	Shankar, Anuraj H., Morin, Paul, Titus, Richard G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Disease Susceptibility Immunity Immunity, Innate Interferon Type I - administration & dosage Interferon Type I - pharmacology Interferon-alpha - biosynthesis Interferon-alpha - genetics Interferon-alpha - immunology Interferon-beta - biosynthesis Interferon-beta - genetics Interferon-beta - immunology Interferon-α Leishmania major Leishmania major - immunology Leishmaniasis, Cutaneous - immunology Lipopolysaccharides - pharmacology Lm, Leishmania major Macrophage Macrophage Activation Macrophages, Peritoneal - immunology Macrophages, Peritoneal - metabolism Macrophages, Peritoneal - parasitology Mice Mice, Inbred BALB C Mice, Inbred C57BL Mouse MØ, macrophage Nitric Oxide - biosynthesis Protozoan parasite Recombinant Proteins Th1 Cells - immunology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!