Identification of β-Amyloid-Responsive Genes by RNA Differential Display: Early Induction of a DNA Damage-Inducible Gene, gadd45

Alzheimer's disease is a neurodegenerative disorder characterized by the extracellular deposition in the brain of amyloid β-peptide (Aβ), presumed to play a pathogenic role. However, the precise molecular mechanisms of its neurotoxicity are not fully understood. Recent studies have suggested th...

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Veröffentlicht in:Experimental neurology 1999-07, Vol.158 (1), p.206-213
Hauptverfasser: Santiard-Baron, Dominique, Gosset, Philippe, Nicole, Annie, Sinet, Pierre-Marie, Christen, Yves, Ceballos-Picot, Irene
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Sprache:eng
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