Possible Interrelationship between Changes in F-actin and Myosin II, Protein Phosphorylation, and Cell Volume Regulation in Ehrlich Ascites Tumor Cells

Osmotic shrinkage of Ehrlich ascites tumor cells (EATC) elicited translocation of myosin II from the cytosol to the cortical region, and swelling elicits concentration of myosin II in the Golgi region. Rho kinase and p38 both appeared to be involved in shrinkage-induced myosin II reorganization. In...

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Veröffentlicht in:	Experimental cell research 2002-07, Vol.277 (1), p.57-73
Hauptverfasser:	Pedersen, S.F., Hoffmann, E.K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Actins - metabolism Amides - pharmacology Animals Antibodies - immunology Azepines - pharmacology blebbing Carcinoma, Ehrlich Tumor Cell Size Enzyme Activation F-actin Isotonic Solutions Mice MLCK myosin II Myosin Type II - immunology Myosin Type II - metabolism Naphthalenes - pharmacology NHE1 Osmosis osmotic Oxazoles - pharmacology p38 Phosphoprotein Phosphatases - antagonists & inhibitors Phosphorylation PKC Protein Isoforms - immunology Protein-Serine-Threonine Kinases - antagonists & inhibitors Protein-Serine-Threonine Kinases - metabolism Pyridines - pharmacology Rho kinase serine/threonine phosphatase Signal Transduction Sodium-Hydrogen Exchangers - metabolism Tumor Cells, Cultured
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