Heterogeneity in the HeLa Cell Cycle Response to UVC Analyzed by the BrdUrd Two-Parameter Method

Using pulse, pulse-chase, and continuous bromodeoxyuridine (BrdUrd) labeling schedules, the effects of 11 Jm -2 of UVC on cell cycling of HeLa cultures were analyzed. The fine resolution of the bivariate DNA distribution method allowed precise quantitation of the grossly perturbed cell distribution...

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Veröffentlicht in:	Experimental cell research 1994-06, Vol.212 (2), p.176-189
Hauptverfasser:	Wang, X-Q., Ellem, K.A.O.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Bromodeoxyuridine Cell Cycle - radiation effects Cell cycle, cell proliferation Cell physiology DNA - biosynthesis DNA Damage - radiation effects Dose-Response Relationship, Radiation Fundamental and applied biological sciences. Psychology HeLa Cells - radiation effects Humans Molecular and cellular biology S Phase Ultraviolet Rays
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