Overexpression of anAgouticDNA in the Skin of Transgenic Mice Recapitulates Dominant Coat Color Phenotypes of Spontaneous Mutants

The classical mouse fancyAgoutigene is responsible for the wild-type coat color where hairs are banded black and yellow. TheAgoutigene encodes a 131-amino-acid secreted protein product that regulates phaeomelanin synthesis by melanocytes in mice. Mice with a dominant mutation at this locus,Ay, devel...

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Veröffentlicht in:Developmental biology 1996-01, Vol.173 (1), p.162-173
Hauptverfasser: Kucera, Gary T., Bortner, Donna M., Rosenberg, Michael P.
Format: Artikel
Sprache:eng
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