Induction of CD25 expression in human B lymphocytes by pharmacological activators of cellular signalling pathways

IL-4 promotes simultaneous expression of both the CD23 and CD25 antigens in resting human B lymphocytes in a dose-dependent manner. Simultaneous three-colour flow cytometric analysis rcvealed that CD19 +/CD23 +/CD25 +triple-positive cells were derived from a CD19 +/CD23 −/CD25 −pool, and that induct...

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Veröffentlicht in:	Cytokine (Philadelphia, Pa.) Pa.), 1996-04, Vol.8 (4), p.305-312
Hauptverfasser:	McKay, Catriona E., Cushley, William
Format:	Artikel
Sprache:	eng
Schlagworte:	B lymphocytes B-Lymphocytes - drug effects B-Lymphocytes - immunology Calcium - blood Chelating Agents Humans IL-2 receptors IL-4 Interleukin-4 - pharmacology Phorbol Esters - pharmacology Receptors, IgE - biosynthesis Receptors, Interleukin-2 - biosynthesis signal transduction Signal Transduction - drug effects Signal Transduction - immunology Up-Regulation
Online-Zugang:	Volltext
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