Increased Plasma Thrombospondin-1 (TSP-1) Levels Are Associated with the TNFα-308A Allele in Children with Juvenile Dermatomyositis

Vascular occlusion is more frequent in children with juvenile dermatomyositis (JDM) who have the TNFα-308A allele. One of the potent anti-angiogenic factors is thrombospondin-1 (TSP-1). This study investigated the association of the TNFα-308A allele with circulating levels of angiogenic mediators, T...

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Veröffentlicht in:	Clinical immunology (Orlando, Fla.) Fla.), 2002-06, Vol.103 (3), p.260-263
Hauptverfasser:	Lutz, Jennica, Huwiler, Kristin G., Fedczyna, Tamara, Lechman, Toula S., Crawford, Susan, Kinsella, T.Randell, Pachman, Lauren M.
Format:	Artikel
Sprache:	eng
Schlagworte:	and juvenile dermatomyositis Biological and medical sciences Medical sciences platelet factor 4 Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis thrombospondin-1 TNFα-308A vascular occlusion
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