Prostaglandin J2 Inhibition of Mesangial Cell iNOS Expression

Mesangial cells from MRL/lpr mice, a model of lupus, overproduce nitric oxide (NO) compared to controls. J series prostaglandins (PG) and thiazolidinediones block LPS stimulation of NO production via the activation of peroxisome proliferator–activator receptor-γ (PPAR-γ) in macrophages but utilize a...

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Veröffentlicht in:	Clinical immunology (Orlando, Fla.) Fla.), 2001-03, Vol.98 (3), p.337-345
Hauptverfasser:	Reilly, Christopher M., Oates, James C., Sudian, Johnny, Crosby, Michelle B., Halushka, Perry V., Gilkeson, Gary S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences General aspects Immunopathology lupus Medical sciences mesangial cell nitric oxide PPAR-γ prostaglandin J2
Online-Zugang:	Volltext
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