OVEREXPRESSION OF THE TYPE II TRANSFORMING GROWTH FACTOR-β RECEPTOR INHIBITS FIBROBLAST PROLIFERATION AND ACTIVATES EXTRACELLULAR SIGNAL REGULATED KINASE AND C-JUN N-TERMINAL KINASE

Transforming growth factor-β (TGF-β) is a bimodal regulator of cellular growth. The cellular effects of TGF-β depend on the intensity of signals emanating from TGF-β receptors. Low levels of receptor activity are sufficient to stimulate cell proliferation, while higher degrees of receptor activation...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Cell biology international 2002-02, Vol.26 (2), p.165-174
Hauptverfasser:	Goldberg, Howard J., Huszár, Tamás, Mózes, Miklós M., Rosivall, László, Mucsi, István
Format:	Artikel
Sprache:	eng
Schlagworte:	cell proliferation fibroblast mitogen activated protein kinase transforming growth factor-beta
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!