Novel Concurrent Synthesis of Side-Chain Analogues of Vitamins D2 and D3: 24,24-Dihomo-25-hydroxycholecalciferol and (22E)-22-Dehydro-24,24-dihomo-25-hydroxycholecalciferol

A novel method for the preparation of side-chain extended analogues of vitamins D is described. Both 24,24-dihomo- and (22E)-22-dehydro-24,24-dihomo-25-hydroxycholecalciferols were efficiently prepared from the same intermediates, i.e., the phenyltriazolinedione adduct of previtamin D with a C-22 al...

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Veröffentlicht in:Bioorganic chemistry 1993-03, Vol.21 (1), p.13-23
Hauptverfasser: Kutner, A., Chodynski, M., Halkes, S.J., Brugman, J.
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Sprache:eng
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